Diastolic Ventricular Function in Primary and Secondary Hypertrophy: The Influence of Verapamil

  • W. H. Bleifeld


Left ventricular diastolic function is of clinical importance [1], because disturbed relaxation results in impaired left ventricular filling and an increase of left ventricular filling pressure with breathlessness during exercise or at rest. Although hypertrophy in highly trained athletes does not appear to be accompanied by abnormalities of systolic or diastolic function as evaluated from the end-diastolic pulmonary artery pressure [2], patients with left ventricular hypertrophy due to pressure overload or primary myocardial disease usually manifest increased filling pressure and, depending on the degree of their disease, may exhibit clinical signs of left heart failure.


Diastolic Function Left Ventricular Filling Stroke Volume Index Filling Period Left Ventricular Outflow Tract Obstruction 
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© Martinus Nijhoff Publishing 1987

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  • W. H. Bleifeld

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