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Ejection, Filling and Diastasis during Transluminal Occlusion in Man: Consideration on Global and Regional Left Ventricular Function

  • Patrick W. Serruys
  • William Wijns
  • Federico Piscione
  • Pim de Feyter
  • Paul G. Hugenholtz

Abstract

An extensive literature exists that describes the acute changes in hemodynamics and left ventricular function following coronary occlusion in animals [1–4]. Much less, however, is known in humans. Extrapolating results from animals to humans is potentially difficult, because in humans preexisting atherosclerotic coronary disease and a unique distribution of collateral circulation [5–7] may influence the findings. Until recently, measurement of left ventricular geometry and hemodynamics early after an abrupt occlusion of a major coronary artery has not been feasible in humans. Percutaneous transluminal coronary angioplasty (PTCA), however, now provides a unique opportunity to study the time course of these variables during the transient interruption of coronary flow in the balloon occlusion sequence in patients with single-vessel disease and without angiographically demonstrable collateral circulation [8–10].

Keywords

Coronary Occlusion Left Atrial Pressure Peak Filling Rate Wall Displacement Ischemic Segment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing 1987

Authors and Affiliations

  • Patrick W. Serruys
  • William Wijns
  • Federico Piscione
  • Pim de Feyter
  • Paul G. Hugenholtz

There are no affiliations available

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