Diastolic Function during Exercise-Induced Ischemia in Man

  • John D. Carroll
  • Otto M. Hess
  • Hans Peter Krayenbuehl


Diastolic pressures frequently increase dramatically during ischemia. The mechanism for the pressure increase has been the subject of many clinical and experimental studies [1–5]. Impaired relaxation has been shown in humans during pacing-induced ischemia [2]. The alterations in left ventricular pressure decay may be important in elevating diastolic pressures, producing the upward shift in the diastolic pressure-volume relation, and impairing the time course and extent of left ventricular filling.


Upward Shift Ischemia Group Peak Filling Rate Filling Period Bypass Group 
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Copyright information

© Martinus Nijhoff Publishing 1987

Authors and Affiliations

  • John D. Carroll
  • Otto M. Hess
  • Hans Peter Krayenbuehl

There are no affiliations available

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