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Influence of Pressure and Volume Overload on Diastolic Compliance

  • H. P. Krayenbuehl
  • O. M. Hess
  • M. Ritter
  • J. Schneider
  • E. S. Monrad
  • J. Grimm

Abstract

Traditionally, the passive diastolic properties of the intact ventricle are assessed from the diastolic portion of the pressure-volume or pressure-length relationship. Compliance of the ventricular chamber refers to the ratio of change in volume (dV) to a change in pressure (dP). The reversed ratio represents chamber stiffness (dP/dV). The relationship between P and V throughout diastole is curvilinear. It is popular to fit the P-V data to an exponential relation, although in many instances (and also in pressure and volume overload) the observed P-V coordinates may clearly deviate from a true exponential relationship. The slope of the pressure-volume relation is termed the constant of chamber stiffness and represents a nonnormalized quantity of diastolic stiffness.

Keywords

Aortic Valve Aortic Stenosis Aortic Valve Replacement Aortic Valve Disease Myocardial Stiffness 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing 1987

Authors and Affiliations

  • H. P. Krayenbuehl
  • O. M. Hess
  • M. Ritter
  • J. Schneider
  • E. S. Monrad
  • J. Grimm

There are no affiliations available

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