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Arenavirus Ultrastructure and Morphogenesis

  • Richard W. Compans
Chapter
Part of the The Viruses book series (VIRS)

Abstract

Although lymphocytic choriomeningitis (LCM) virus was identified as an infectious agent during the early decades of virology research (Armstrong and Lillie, 1934; Traub, 1935), no information on its structure or classification was obtained until many years had elapsed. The development of cell culture systems for virus growth and improved preparative procedures for electron microscopy enabled the initial identification of characteristic LCMV particles in thin sections of virus-infected cells (Dalton et al., 1968). Soon thereafter, other viruses belonging to the Tacaribe complex were found to have a similar morphology (Murphy et al.,1970), leading to the classification of these agents in a new virus family (Rowe et al.,1970). Subsequently, some additional information has been obtained on the structure of the internal components of arena-viruses. This chapter reviews our current knowledge of the virion structure and the process of viral morphogenesis for this family of viruses.

Keywords

Envelop Virus Virus Assembly Lymphocytic Choriomeningitis Nucleoprotein Complex Lymphocytic Choriomeningitis Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Richard W. Compans

There are no affiliations available

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