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Coronaviruses pp 389-391 | Cite as

Regulation of the Expression of Intercellular Adhesion Molecule-1 (ICAM-1) and the Putative Adhesion Molecule Basigin on Murine Cerebral Endothelial Cells by MHV-4 (JHM)

  • Jeymohan Joseph
  • Robert L. Knobler
  • Fred D. Lublin
  • Frank R. Burns
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 342)

Abstract

Cerebral vascular endothelial cells are integral components of the blood-brain barrier and are believed to be an important site which can restrict infection of the central nervous system by viruses and other pathogens. A potential role of cerebral vascular endothelial cells in resisting CNS infection relates to the expression of lymphocyte-endothelial adhesion molecules which could impact on the generation of anti-viral immune reactivity.

Keywords

Endothelial Cell Northern Analysis Brain Endothelial Cell Immunoglobulin Superfamily Cerebral Endothelial Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    Rupnick, M.A., Carey, A., and Williams, S.K., 1988, In Vitro Cell. Dev. Biol., 24:435.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Jeymohan Joseph
    • 1
  • Robert L. Knobler
    • 1
  • Fred D. Lublin
    • 1
  • Frank R. Burns
    • 2
  1. 1.Division of NeuroimmunologyJefferson Medical CollegePhiladelphiaUSA
  2. 2.Department of NeurologyUniversity of Pennsylvania Medical CenterPhiladelphiaUSA

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