Analysis of the Sialic Acid-Binding Activity of Transmissible Gastroenteritis Virus

  • B. Schultze
  • L. Enjuanes
  • G. Herrler
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 380)


Porcine transmissible gastroenteritis virus (TGEV) has been shown to agglutinate erythrocytes using a2,3-linked sialic acid on the cell surface as binding site. The hemagglutinating activity requires the pretreament of virus with neuraminidase. We obtained evidence that TGEV recognizes not only N-acetylneuraminic acid but also N-glycoloylneuraminic acid, a sialic acid present on many porcine cells.


Sialic Acid Infectious Bronchitis Virus Hemagglutinating Activity Hemagglutination Assay Neuraminic Acid 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • B. Schultze
    • 1
  • L. Enjuanes
    • 2
  • G. Herrler
    • 1
  1. 1.Institut für VirologiePhilipps-Universität MarburgMarburgGermany
  2. 2.Centro De Biologia MolecularCSIC Universidad AutonomaMadridSpain

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