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TRIM Proteins in Development

  • Francesca Petrera
  • Germana Meroni
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 770)

Abstract

TRIM proteins play important roles in several patho-physiological processes. Their common activity within the ubiquity lation pathway makes them amenable to a number of diverse biological roles. Many of the TRIM genes are highly and sometimes specifically expressed during embryogenesis, it is therefore not surprising that several of them might be involved in developmental processes. Here, we primarily discuss the developmental implications of two subgroups of TRIM proteins that conserved domain composition and functions from their invertebrate ancestors. The two groups are: the TRIM-NHL proteins implicated in miRNA processing regulation and the TRIM-FN3 proteins involved in ventral midline development.

Keywords

Neural Tube Closure Cell Cycle Exit Tripartite Motif Synaptic Vesicle Exocytosis Trim Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Landes Bioscience and Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Francesca Petrera
    • 1
  • Germana Meroni
    • 1
  1. 1.Cluster in BiomedicineCBM S.c.r.lTriesteItaly

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