Skip to main content

The Role of Twinning Programs and Telemedicine in Pediatric Oncology

  • Chapter
  • First Online:
Pediatric Hematology-Oncology in Countries with Limited Resources

Abstract

Childhood cancer survival rates in highly developed countries have risen remarkably over the past 50 years from <10 % to over 80 %. This has been achieved as a result of early and precise diagnosis, effective and targeted treatment, and adequate supportive care. This contrasts with the situation in low- and middle-income countries (LMICs) where overall survival rates are <20 %. In order to address this gross inequity and improve chances of survival of children with cancer, a number of twinning programs, linking pediatric oncology units in resource-rich countries with units in countries with limited resources, have been established.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Notes

  1. 1.

    Guidelines adapted from St Jude: International Outreach Program—Guide to Establishing a Pediatric Oncology Twinning Program.

  2. 2.

    Many different definitions are used in the literature. WHO [1] adopts a broader definition, encompassing general eHealth: telemedicine is “the delivery of health care services, where distance is a critical factor, by all health care professionals using information and communication technologies for the exchange of valid information for diagnosis, treatment and prevention of disease and injuries, research and evaluation, and for the continuing education of health care providers, all in the interest of advancing the health of individuals and their communities.”

References

  1. Wilimas JA, Ribeiro RC. Pediatric hematology-oncology outreach for developing countries. Hematol Oncol Clin North Am. 2001;15(4):775–87, x.

    Google Scholar 

  2. Howard SC, Metzger ML, Wilimas JA, Quintana Y, Pui CH, Robison LL, Ribeiro RC. Childhood cancer epidemiology in low-income countries. Cancer. 2008;112(3):461–72.

    Article  PubMed  Google Scholar 

  3. Magrath I, et al. Pediatric oncology in less developed countries. In: Pizzo PA, Poplack DG, editors. Principles and practice of pediatric oncology. Philadelphia, PA: Lippincott; 1993. p. 1225–51.

    Google Scholar 

  4. Ribeiro RC, Pui CH. Saving the children–improving childhood cancer treatment in developing countries. N Engl J Med. 2005;352(21):2158–60.

    Article  PubMed  CAS  Google Scholar 

  5. Kellie SJ, Howard SC. Global child health priorities: what role for paediatric oncologists? Eur J Cancer. 2008;44:2388–96.

    Article  PubMed  Google Scholar 

  6. Wagner HP, Antic V. The problem of pediatric malignancies in the developing world. Ann N Y Acad Sci. 1997;824:193–204.

    Article  PubMed  CAS  Google Scholar 

  7. Masera G, Baez F, Biondi A, et al. Bridging the childhood cancer mortality gap between economically developed and low income countries: lessons from the MISPHO experience. In: Tannenberg S, Cavalli F, Pannuti F, editors. Cancer in developing countries. The great challenge for oncology in the 21st century. Muenchen: Zuckschwerdt; 2004. p. 42–60.

    Google Scholar 

  8. Wagner H. Alliances in pediatric oncology: where do we go from here? Med Pediatr Oncol. 2001;36(2):310–1.

    Article  PubMed  CAS  Google Scholar 

  9. The Montevideo Document. SIOP News. 1997;17:32.

    Google Scholar 

  10. Baez F, Ocampo E, Conter V, et al. Treatment of childhood Hodgkin’s disease with COPP or COPP-ABV (hybrid) without radiotherapy in Nicaragua. Ann Oncol. 1997;8:247–50.

    Article  PubMed  CAS  Google Scholar 

  11. Baez F, Pillon M, Manfredini L, et al. Treatment of pediatric non-Hodgkin lymphomas in a country with limited resources: results of the first national protocol in Nicaragua. Pediatr Blood Cancer. 2008;50:148–52.

    Article  PubMed  CAS  Google Scholar 

  12. Baez F, Fossati Bellani F, Ocampo E, et al. Treatment of childhood Wilms’ tumor without radiotherapy in Nicaragua. Ann Oncol. 2002;13:944–8.

    Article  PubMed  CAS  Google Scholar 

  13. Masera G, Baez Lacayo F, Malta Corea A, et al. Pediatric oncology in developing countries: a cooperative program in Nicaragua. Ann Oncol. 1993;4:37–40.

    Article  PubMed  CAS  Google Scholar 

  14. SIOP. 43rd Congress of the International Society of Paediatric Oncology (SIOP) 2011, Auckland, New Zealand, 28th–30th October 2011. Abstracts Pediatr Blood Cancer. 2011;57(5):705–897. doi:10.1002/pbc.23299.

  15. Masera G, Baez F, et al. North–south twinning in paediatric haemato-oncology: the La Mascota programme, Nicaragua. Lancet. 1998;352(9144):1923–6.

    Article  PubMed  CAS  Google Scholar 

  16. D’Angio GJ. The La Mascota project. J Pediatr Hematol Oncol. 2009;31(10):709.

    Article  PubMed  Google Scholar 

  17. Masera G. Bridging the childhood cancer mortality gap between economically developed and low-income countries. J Pediatr Hematol Oncol. 2009;31(10):710–2.

    Article  PubMed  Google Scholar 

  18. Edefonti A, Montini G, Castellon M; for the Nicaraguan Network of Pediatric Nephrology—NINEPEN. Comprehensive cooperative project for children with renal disease in Nicaragua. Clin Nephrol. 2010;74 Suppl. 1:S119–25.

    Google Scholar 

  19. Sala A, Barr RD, Masera G, MISPHO Consortium. A survey of resources and activities in the MISPHO family of institutions in Latin America: a comparison of two eras. Pediatr Blood Cancer. 2004;43(7):758–64.

    Article  PubMed  Google Scholar 

  20. Howard SC, Marinoni M, Castillo L, Bonilla M, Tognoni G, Luna-Fineman S, Antillon F, Valsecchi MG, Pui CH, Ribeiro RC, Sala A, Barr RD, Masera G, MISPHO Consortium Writing Committee. Improving outcomes for children with cancer in low-income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)-Part I. Pediatr Blood Cancer. 2007;48(3):364–9.

    Article  PubMed  Google Scholar 

  21. Howard SC, Ortiz R, Baez LF, Cabanas R, Barrantes J, Fu L, Peña A, Samudio A, Vizcaino M, Rodríguez-Galindo C, Barr RD, Conter V, Biondi A, Masera G, MISPHO Consortium Writing Committee. Protocol-based treatment for children with cancer in low income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)—part I. Pediatr Blood Cancer. 2007;48(4):486–90.

    Article  PubMed  Google Scholar 

  22. Valsecchi MG, Tognoni G, Bonilla M, Moreno N, Baez F, Pacheco C, Hernandez AP, Antillon-Klussmann F, Machin S, Cabanas R, Navarrete M, Nieves R, De Lorenzo P, Masera G, Monza’s International School of Paediatric Hematology-Oncology. Clinical epidemiology of childhood cancer in Central America and Caribbean countries. Ann Oncol. 2004;15(4):680–5.

    Article  PubMed  CAS  Google Scholar 

  23. Rohatiner A. Keynote comment: not just an exercise in solidarity. Lancet Oncol. 2005;6(11):818–9.

    Article  PubMed  Google Scholar 

  24. Antillon F, Baez FL, Barr R, Barrantes Zamorra JC, Carrasco LF, Moreno B, Bonilla MM, Tognoni G, Valsecch MG, Howard S, Ribeiro RC, Masera G. AMOR: a proposed cooperative effort to improve outcomes of childhood cancer in Central America. Pediatr Blood Cancer. 2005;45(2):107–10.

    Article  PubMed  Google Scholar 

  25. Quintana Y, Nambayan A, Ribeiro R, et al. Cure4Kids—building online learning and collaboration networks. AMIA Annu Symp Proc. 2003;2003:978.

    Google Scholar 

  26. Israëls T, Chirambo C, Caron H, de Kraker J, Molyneux E, Reis R. The guardians’ perspective on paediatric cancer treatment in Malawi and factors affecting adherence. Pediatr Blood Cancer. 2008;51:639–42.

    Article  PubMed  Google Scholar 

  27. Hesseling PB, Broadhead R, Molyneux E, Borgstein E, Schneider JW, Louw M, Mansvelt EP, Wessels G. Malawi pilot study of Burkitt lymphoma treatment. Med Pediatr Oncol. 2003;41:532–40.

    Article  PubMed  Google Scholar 

  28. Mostert S, Sitaresmi M, Gundy C. PK020 influence of socioeconomic status on childhood acute lymphoblastic leukaemia treatment in Indonesia [abstract]. Pediatr Blood Cancer. 2006;47:489.

    Google Scholar 

  29. Hunger SP, Sung L, Howard SC. Treatment strategies and regimens of graduated intensity for childhood acute lymphoblastic leukemia in low-income countries: a proposal. Pediatr Blood Cancer. 2009;52(5):559–65. doi:10.1002/pbc.21889.

    Article  PubMed  Google Scholar 

  30. Arora RS, Eden T, Pizer B. The problem of treatment abandonment in children from developing countries with cancer. Pediatr Blood Cancer. 2007;49(7):941–6.

    Article  PubMed  Google Scholar 

  31. Sitaresmi MN, Mostert S, Schook RM, Sutaryo, Veerman AJ. Treatment refusal and abandonment in childhood acute lymphoblastic leukemia in Indonesia: an analysis of causes and consequences. Psychooncology. 2010;19(4):361–7. doi:10.1002/pon.1578.

    Article  PubMed  Google Scholar 

  32. Spinetta JJ, Masera G, Eden T, et al. Refusal, non-compliance, and abandonment of treatment in children and adolescents with cancer: a report of the SIOP Working Committee on Psychosocial Issues in Paediatric Oncology. Med Pediatr Oncol. 2002;38:114–7.

    Article  PubMed  Google Scholar 

  33. World Health Organization, Telemedicine: opportunities and developments in member states; report on the Second Survey on eHealth, 2010 (Global Observatory for eHealth Series 2). Available from http://www.who.int/goe/publications/goe_telemedicine_2010.pdf

  34. ITU. Measuring the information society; 2012. Available from http://www.itu.int/ITU-D/ict/publications/idi/material/2012/MIS2012_without_Annex_4.pdf

  35. Bellina L, Missoni E. Mobile cell-phones (M-phones) in telemicroscopy: increasing connectivity of isolated laboratories. Diagn Pathol. 2009;4:19.

    Article  PubMed  Google Scholar 

  36. Bellina L, Missoni E. M-learning: mobile phones’ appropriateness and potential for the training of laboratory technicians in limited-resource settings. Health Technol. 2011;1:93–97

    Google Scholar 

  37. http://en.wikipedia.org/wiki/FrontlineSMS

  38. http://en.wikipedia.org/wiki/WhatsApp

  39. http://en.wikipedia.org/wiki/E_Health_Point

  40. http://en.wikipedia.org/wiki/Cure4Kids

  41. http://en.wikipedia.org/wiki/Diabetes_Hands_Foundation

  42. http://en.wikipedia.org/wiki/Ning_(website)

Download references

Acknowledgments

We would like to thank the following for their contribution to the project “La Mascota”: Fondazione CARIPLO, Comitato Maria Letizia Verga, Fondazione Tettamanti, Fondazione Zegna, AMCA (Bellinzona, Switzerland), CONANCA and MAPANICA (Nicaragua), the HMJR “La Mascota” Hospital (Managua), St. Jude Children’s Research Hospital (SJCRH, Memphis, USA), and the Pediatric Oncology Group of Ontario (POGO).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Valentino Conter M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Science+Business Media New York

About this chapter

Cite this chapter

Conter, V., Polillo, R., Brivio, E., Faravelli, A., Masera, G. (2014). The Role of Twinning Programs and Telemedicine in Pediatric Oncology. In: Stefan, D., Rodriguez-Galindo, C. (eds) Pediatric Hematology-Oncology in Countries with Limited Resources. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3891-5_4

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-3891-5_4

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-3890-8

  • Online ISBN: 978-1-4614-3891-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics