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Mechanisms of Selective CA Antagonist-Induced Vasodilation

  • C. Van Breemen
  • C. Cauvin
  • O. Hwang
  • P. Leyten
  • S. Lukeman
  • K. Meisheri
  • K. Saida
  • H. Yamamoto
Chapter
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 39)

Abstract

Vascular smooth muscle is the primary target organ for Ca antagonist (CAt) therapy. It is now well established that CAts bind to and block excitable channels in the cell membrane (1). The question which remains to be answered is why are these agents selective for certain blood vessels and certain modes of activation.

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Copyright information

© Martinus Nijhoff Publishing, Boston 1984

Authors and Affiliations

  • C. Van Breemen
  • C. Cauvin
  • O. Hwang
  • P. Leyten
  • S. Lukeman
  • K. Meisheri
  • K. Saida
  • H. Yamamoto

There are no affiliations available

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