Determinants of Subjective Attributes of Normal Cutaneous Sensation and of Paresthesiae from Ectopic Nerve Impulse Generation

  • José Ochoa
  • Erik Torebjörk
  • William Culp
Part of the Wenner-Gren Center International Symposium Series book series (EMISS, volume 12)


Upon discovering the internal language of the nervous system, in the mid 1920’s, Adrian and Zotterman (1926) immediately realized that the laconic messages transmitted as monotonous codes in which the only variable was impulse frequency, were probably decoded as the intensity of a particular sensory quality. Indeed, in their cats, intensity of a mechanical stimulus was reflected as frequency afferent discharge, and so it took little imagination on the part of those introspective sensory physiologists to equate the receptor response feature with the subjective magnitude attribute.


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Copyright information

© The Wenner-Gren Center 1984

Authors and Affiliations

  • José Ochoa
    • 1
  • Erik Torebjörk
    • 2
  • William Culp
    • 3
  1. 1.Department of NeurologyUniversity of Wisconsin Medical SchoolMadisonUSA
  2. 2.Department of Clinical NeurophysiologyAcademic HospitalUppsalaSweden
  3. 3.Department of BiochemistryDartmouth Medical SchoolHanoverUSA

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