Sensibility Abnormalities in Neuralgic Patients Studied By Thermal and Tactile Pulse Stimulation

  • Heinrich Fruhstorfer
  • Ulf Lindblom
Part of the Wenner-Gren Center International Symposium Series book series (EMISS, volume 12)


Six patients with neuralgia and disturbed thermosensibility were examined with graded thermal and mechanical pulses which were applied in the pain area and in contralateral normal skin for comparison. In five patients stimuli in the non-noxious range evoked pain. Reaction times were modality specific which suggests that the pathophysiology of the abnormal stimulus-evoked pain sensations was central although the original lesion was in the peripheral nerve. With repetitive stimulation habituation of sensation was observed in five patients and abnormal summation in two. It was concluded that pulsed natural stimuli may be valuable in further analyses of the mechanisms of sensory dysfunction and pain, and possibly also in clinical evaluation.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Fruhstorfer, H., Detering, I. (1974). A simple thermode for rapid temperature changes. Pflügers Arch. ges. Physiol., 349, 83–85CrossRefGoogle Scholar
  2. Fruhstorfer, H., Lindblom, U., Schmidt, W. G. (1976). Method for quantitative estimation of thermal thresholds in patients. J. Neurol. Neurosurg. Psychiat., 39, 1071–1075PubMedCentralPubMedCrossRefGoogle Scholar
  3. Lindblom, U. (1974). Touch perception threshold in human glabrous skin in terms of displacement amplitude on stimulation with single mechanical pulses. Brain Res., 82, 205–210PubMedCrossRefGoogle Scholar
  4. Lindblom, U., Verillo, R. T. (1979). Sensory functions in chronic neuralgia. J. Neurol. Neurosurg. Psychiat., 42, 422–435PubMedCentralPubMedCrossRefGoogle Scholar
  5. Merskey, H. (1982). Pain terms: A supplementary note. Pain, 14, 205–206CrossRefGoogle Scholar

Copyright information

© The Wenner-Gren Center 1984

Authors and Affiliations

  • Heinrich Fruhstorfer
    • 1
  • Ulf Lindblom
    • 2
  1. 1.Institute of PhysiologyUniversity of MarburgMarburgGermany
  2. 2.Department of NeurologyKarolinska HospitalStockholmSweden

Personalised recommendations