Abstract
In contrast to our incomplete understanding of many of the rheumatic diseases, information is more abundant about the pathogenesis of those caused by recognized infectious agents. Yet even here, great gaps exist in our ability to identify the presence of these agents promptly and to cope with their virulence. More striking is our ignorance of the complex immune apparatus that the host invokes to counter their attack.
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References
Aho, K., 1983, Yersinia reactive arthritis, Br. J. Rheumatol. 22 (Suppl. 2):41–5.
Aho, K., and Raunio, V., 1982, EB-virus and rheumatoid arthritis:New insights into their interrelation, Med. Biol. 60:49–52.
Alarcon, G. S., Bocanegra, T. S., Gotuzzo, E., Hinostroza, S., Carrillo, C., Vasey, F. B., Germain, B. F., and Espinoza, L. R., 1981, Reactive arthritis associated with brucellosis:HLA studies, J. Rheumatol. 8:621–625.
Allen, J. B., Blatter, D., Calandra, G. B., and Wilder, R. L., 1983, Sex hormonal effects on the severity of streptococcal cell wall-induced polyarthritis in the rat, Arthritis Rheum. 26:560–563.
Ansell, B. M., and Wigley, R. A. D., 1964, Arthritic manifestations in regional enteritis, Ann. Rheum. Dis. 23:64–12.
Argen, R. J., Wilson, C. H., and Wood, P., 1966, Suppurative arthritis:Clinical features of 42 cases, Arch. Intern. Med. 117:661–671.
Arnett, F. C., 1979, Incomplete Reiter’s syndrome:Clinical comparisons with classical triad, Ann. Rheum. Dis. 38 (Suppl. l):73–78.
Arnett, F. C., Jr., Hochberg, M. C., and Bias, W. B., 1977, Cross-reactive HLA antigens in B27-negative Reiter’s syndrome and sacroiliitis, Johns Hopkins Med. J. 141:193–197.
Arthur, R. E., Stern, M., Galeazzi, M., Basdassare, A. R., Weiss, T. D., Rogers, J. R., and Zuckner, J., 1983, Synovial fluid lactic acid in septic and nonseptic arthritis, Arthritis Rheum. 26:1499–1505.
Atcheson, S. G., and Ward, J. R., 1978, Acute hematogenous osteomyelitis progressing to septic synovitis and eventual pyrarthrosis:The vascular pathway, Arthritis Rheum. 21:968–971.
Avakian, H., Welsh, J., Ebringer, A., and Entwistle, C. C., 1980, Ankylosing spondylitis, HLA-B27 and Klebsiella. II. Cross-reactivity studies with human tissue typing sera, Br. J. Exp. Pathol. 61:92–96.
Bauer, W., and Engleman, E. P., 1942, A syndrome of unknown etiology characterized by urethritis, conjunctivitis and arthritis (so-called Reiter’s disease), Trans. Assoc. Am. Physicians 57:307–313.
Bayer, A. S., Chow, A. W., Louie, J. S., Nies, K. M., and Guze, L. B., 1977, Gram-negative bacillary septic arthritis:Clinical, radiographic, therapeutic and prognostic features, Semin. Arthritis Rheum. 17:503–510.
Brandt, K. D., Cathcart, E. S., and Cohen, A. S., 1974, Gonococcal arthritis:Clinical features correlated with blood, synovial fluid and genitourinary cultures, Arthritis Rheum. 17:503–510.
Braude, A. I., Jones, J. L., and Douglas, H., 1963, The behavior of Escherichia coli endotoxin (somatic antigen) during infectious arthritis, J. Immunol. 90:297–311.
Brenner, M. B., Kobayashi, S., Weisenhutter, C. W., Huberman, A. K., Bales, P., and Yu, D. T. Y., 1984, In vitro T lymphocyte proliferative response to Yersinia enterocolitica in Reiter’s syndrome:Lack of response in other HLA-B27 positive individuals, Arthritis Rheum. 27:250–257.
Calabro, J. J., 1980, The spondyloarthropathies: An overview, Scand. J. Rheumatol. 9 (Suppl. 32):21–24.
Calin, A., Kaslow, R. A., Simon, D., Ryder, R. P., Kaye, R., and Dritz, S., 1979, Reiter’s syndrome and the seroepidemiology of Shigella, Ann. Rheum. Dis. 38:190.
Calin, A., Marder, A., Becks, E., and Burns, T., 1983, Genetic differences between B27 positive patients with ankylosing spondylitis and B27 positive healthy controls, Arthritis Rheum. 26:1460–1464.
Canoso, J. J., and Sheckman, P. R., 1979, Septic subcutaneous bursitis:Report of sixteen cases, J. Rheumatol. 6:96–102.
Clark, R. L., Cuttino, J. T., Anderle, S. K., Cromartie, W. J., and Schwab, J. H., 1979, Radiologic analysis of arthritis in rats after systemic injection of streptococcal cell walls, Arthritis Rheum. 22:25–35.
Cowling, P., Ebringer, R., Cawdell, D., Ishii, M., and Ebringer, A., 1980, C-reactive protein, ESR and Klebsiella in ankylosing spondylitis, Ann. Rheum. Dis. 39:45–49.
Crider, S. R., Colby, S. D., Miller, L. K., Harrison, W. O., Kerbs, S. B. J., and Berg, S. W., 1984, Treatment of penicillin-resistant Neisseria gonorrhoeae with oral norfloxacin, N. Engl. J. Med. 311:137–140.
Cromartie, W. J., Craddock, J. G., Schwab, J. H., Anderle, S. K., and Yang, C. H., 1977, Arthritis in rats after systemic injection of streptococcal cells or cell walls, J. Exp. Med. 146:1585–1602.
Damian, R. T., 1964, Molecular mimicry: Antigen sharing by parasite and host and its consequences, Am. Nat. 98:129–149.
Dicken, C. H., and Seehafer, J. R., 1979, Bowel bypass syndrome, Arch. Dermatol. 115:837–839.
Duffy, P., Lidsky, M. D., Sharp, J. T., Davis, J. S., Person, D. A., Hollinger, F. B., and Min, K.-W., 1976, Polyarthritis, polyarteritis and Hepatitis B., Medicine (Baltimore) 55:19–37.
Dziarski, R., 1982, Preferential induction of autoantibody secretion in polyclonal activation by petidoglycan and lipopolysaccharide:II. In vivo studies, J. Immunol. 128:1026–1030.
Eagle, H., 1952, Experimental approach to the problem of treatment failure with penicillin:I. Group A streptococcal infection in mice, Am. J. Med. 13:389–399.
Eastmond, J. C., 1983, Gram-negative bacteria and B27 disease, Br. J. Rheumatol. 22 (Suppl. 2):67–74.
Eastmond, C. J., Wilshaw, H. E., Burgess, S. E., Shinebaum, R., Cooke, E. M., and Wright, V., 1980, The frequency of faecal Klebsiella aerogenes in patients with ankylosing spondylitis and controls with respect to individual features of the disease, Ann. Rheum. Dis. 39:118–123.
Ebringer, A., 1978, The link between genes and disease, New Sci. 79:865–867.
Ebringer, A., 1979, Ankylosing spondylitis, immune response genes and molecular mimicry, Lancet 1:1186.
Ebringer, A., 1983, The cross-tolerance hypothesis, HLA-B27 and ankylosing spondylitis, Br. J. Rheumatol. 22 (Suppl. 2):53–66.
Eisenstein, B. I., and Masi, A. T., 1981, Disseminated gonococcal infection (DGI) and gonococcal arthritis (GCA):I. Bacteriology, epidemiology, host factors, pathogen factors, and pathology, Semin. Arthritis Rheum. 10:155–172.
Espinoza, L. R., Vasey, F. B., Oh, J. H., Wilkinson, R., and Osterland, C. K., 1978, Association between HLA-Bw38 and peripheral psoriatic arthritis, Arthritis Rheum. 21:72–75.
Fox, A., Brown, R. G., Anderle, S. K., Chetty, C., Cromartie, W. J., Gooder, H., and Schwab, J. H., 1982, Arthropathic properties related to the molecular weight of peptidoglycan-polysaccharide polymers of streptococcal cell wall, Infect. Immun. 35:1003–1010.
Gallis, H. A., Miller, S. E., and Wheat, R. W., 1966, Degradation of 14-C labelled streptococcal cell walls by egg white lysozyme and lysosomal enzymes, Infect. Immun. 13:1459–1466.
Goldenberg, D. L., 1983, Post-infectious arthritis: A new look at an old concept with particular attention to disseminated gonococcal infection (DGI), Am. J. Med. 74:925–928.
Goldenberg, D. L., and Cohen, A. S., 1976, Acute infectious arthritis: A review of patients with nongonococcal joint infections (with emphasis on therapy and prognosis), Am. J. Med. 60:369–377.
Goldenberg, D. L., Brandt, K. D., Cathcart, E. S., and Cohen, A. S., 1974, Acute arthritis caused by gram negative bacilli: A clinical characterization, Medicine (Baltimore) 53:197–208.
Goldenberg, D. L., Brandt, K. D., Cohen, A. S., and Cathcart, E. S., 1975, Treatment of septic arthritis:Comparison of needle aspiration and surgery as initial modes of joint drainage, Arthritis Rheum. 18:83–90.
Goldenberg, D. L., Chisholm, P. L., and Rice, P. A., 1983, Experimental model of bacterial arthritis: A microbiologic and histopathologic characterization of the arthritis after the intraarticular injection of Neisseria gonorrhoeae, Staphylococcus aureus, group A streptococci and Escherichia coli, J. Rheumatol. 10:5–11.
Goldenberg, D. L., Reed, J. I., and Rice, P. A., 1984, Arthritis in rabbits induced by killed Neisseria gonorrhoeae and gonococcal lipopolysaccharide, J. Rheumatol. 11:3–8.
Greenblatt, J., Boackle, R. J., and Schwab, J. H., 1978, Activation of the alternate complement pathway by peptidoglycan from streptococcal cell wall, Infect. Immun. 19:296–303.
Grumet, F. C., 1983, Monoclonal antibodies to HLA-B27, Br. J. Rheumatol. 22 (Suppl. 2):110–118.
Hawkins, C. F., Farr, M., Morris, C. J., Hoare, A. M., and Williamson, N., 1976, Detection of electron microscopy of rod-shaped organisms in synovial membrane from a patient with the arthritis of Whipple’s disease, Ann. Rheum. Dis. 35:502–509.
Herrick, W. W., and Parkhurst, G. M., 1919, Meningococcus arthritis, Am. J. Med. Sci. 158:473–481.
Hochberg, M. C., Bias, B., and Arnett, F. C., Jr., 1978, Family studies in HLA-B27 associated arthritis, Medicine (Baltimore) 57:463–475.
OecHollingsworth, J. W., and Atkins, E., 1965, Synovial inflammatory response to bacterial endotoxin, Yale J. Biol. Med. 38:241–256.
Hsu, S. H., Chan, M. M., and Bias, W. B., 1981, Genetic control of major histocompatibility complex-linked immune responses to synthetic polypeptides in man, Proc. Natl. Acad. Sci. U.S.A. 78:440–444.
Hughes, W. T., 1977, Infections in the compromised host, Adv. Intern. Med. 22:73–81.
Inman, R. D., Gallegos, K. V., Brause, B. D., Redecha, P. B., and Christian, C. L., 1984, Clinical and microbial features of prosthetic joint infection, Am. J. Med. 77:47–53.
Jarrett, M. P., Grossman, L., Sadler, A. H., and Grayzel, A. I., 1981, The role of arthroscopy in the treatment of septic arthritis, Arthritis Rheum. 24:737–739.
Joysey, V. C., and Wolf, E., 1978, HLA-A, -B, and -C antigens, their serology and cross reaction, Br. Med. Bull. 34:217–222.
Jupiter, J. B., Karchmer, A. W., Lowell, J. D., and Harris, W. H., 1981, Total hip arthroplasty in the treatment of adult hips with current or quiescent sepsis, J. Bone Joint Surg. 63A:194–200.
Kaslow, R. A., 1984, The epidemiology of Yersinia and other reactive arthropathies, in: Epidemiology of the Rheumatic Diseases (R. C. Lawrence and L. E. Shulman, eds.), Gower Medical, New York, London, pp. 89–100.
Kaslow, R. A., Ryder, R. P., and Calin, A., 1979, Search for Reiter’s syndrome after an outbreak of Shigella sonnei dysentery, J. Rheumatol. 6:562–566.
Kasunen, T. U., Kaurenen, O., Martio, J., Pitkänen, J., Pönkä, A., Hortling, L., Aittoniemi, S., Mutru, O., Penttila, O., and Koskimies, S., 1980, Reactive arthritis after Campylobacter jejuni enteritis in patients with HLA-B27, Lancet 1:1312–1313.
Keat, A., 1983, Reiter’s syndrome and reactive arthritis in perspective, N. Engl. J. Med. 309:1606–1615.
Kellgren, J. H., Ball, J., Fairbrother, R. W., and Barnes, K. L., 1958, Suppurative arthritis complicating rheumatoid arthritis, Br. Med. J. 1:1193 - 1200.
Kelly, J. J., and Weisiger, B. B., 1963, The arthritis of Whipple’s disease, Arthritis Rheum. 6:615–632.
Khan, M. A., Kushner, I., and Braun, W. E., 1980, Genetic heterogeneity in primary ankylosing spondylitis, J. Rheumatol. 7:383–386.
LeClerq, S. A., and Russell, A. S., 1984, The risk of sacroiliitis in B27 positive persons: A reappraisal, J. Rheumatol. 11:327 - 329.
Lehman, T. J. A., Allen, J. B., Plotz, P. H., and Wilder, R. L., 1983, Polyarthritis in rats following the systemic injection of Lactobacillus casei cell walls in aqueous suspension, Arthritis Rheum. 26:1259–1265.
Lehman, T. J. A., Allen, J. B., Plotz, P. H., and Wilder, R. L., 1984, Lactobacillus casei cell wall-induced arthritis in rats:Cell wall fragment distribution and persistence in chronic arthritis-susceptible LEW/N and -resistant F344/N rats, Arthritis Rheum. 27:939–942.
Lofgren, R. P., Mahowald, M. L., Peterson, L. R., Jagiella, W. M., Raddatz, D. A., Raskind, J. R., Shafer, R. B., and Gereing, D. N., 1982, Staphylococcal bacteremia in rabbits with antigen induced arthritis, Arthritis Rheum. 25:S83.
London, J. C., 1976, The ecology and taxonomic status of the lactobacilli, Annu. Rev. Microbiol. 30:279–301.
Maizel, H., Rufin, J. M., and Dobbins, W. O., 1970, Whipple’s disease: A review of 19 patients from one hospital and a review of the literature since 1950, Medicine (Baltimore) 49:175–205.
Manicourt, D. H., and Orloff, S., 1982, Gonococcal arthritis-dermatitis syndrome:Study of serum and synovial fluid immune complex levels, Arthritis Rheum. 25:574–578.
McMichael, A., and McDevitt, H. O., 1977, The association between the HLA system and disease, Prog. Med. Genet. 2:39–95.
Nelson, J. D., 1972, The bacterial etiology and antibiotic management of septic arthritis in infants and children, Pediatrics 50:437–440.
Newman, J. H., 1976, Review of septic arthritis throughout the antibiotic era, Ann. Rheum. Dis. 35:198–205.
Norton, W. L., Lewis, D., and Ziff, M., 1966, Light and electron microscopic observations in the synovitis of Reiter’s disease, Arthritis Rheum. 9:747–757.
O’Brien, J. P., Goldenberg, D. L., and Rice, P. A., 1983, Disseminated gonococcal infection: A prospective analysis of 49 patients and a review of pathophysiology and immune mechanism, Medicine (Baltimore) 62:395–406.
Oxelius, J.-A., 1984, Immunoglobulin G (IgG) subclasses and human disease, Am. J. Med. 76 (3A):7–18.
Parant, M., Parant, F., Chedid, L., Yapa, A., Petit, J. F., and Lederer, D., 1979, Fate of the synthetic immunoadjuvant, muramyl dipeptide (14-C-labelled) in the mouse, Int. J. Immunopharmacol. 1:35–41.
Parker, R. H., and Schmid, F. R., 1971, Antibacterial activity of synovial fluid during therapy of septic arthritis, Arthritis Rheum. 14:96–104.
Peltola, H., Kayaty, H., Virtanen, M., Makela, P. H., 1984, Prevention of Hemophilus influenzae type b bacteremic infections with the capsular polysaccharide vaccine, N. Engl. J. Med. 310:1561–1566.
Peterson, B. H., Lee, T. J., Snyderman, R., and Brooks, G. F., 1979, Neisseria meningitidis and Neisseria gonorrhoeae bacteremia associated with C6, C7 or C8 deficiency, Ann. Intern. Med. 90:917–920.
Phemister, D. B., 1924, The effect of pressure on articular surfaces in pyogenic and tuberculous arthritides and its bearing on treatment, Ann. Surg. 80:481–500.
Reed, W. P., Davidson, M. S., and Williams, R. C., Jr., 1976, Complement system in pneumococcal infection, Infect. Immun. 13:1120–1128.
Rittner, C., and Bertrams, J., 1981, On the significance of C2, C4 and factor B polymorphisms in disease, Human Genet. 56:235–247.
Rodey, G. E., Luehrman, L. K., and Thomas, D. W., 1979, In vitro primary immunization of human peripheral blood lymphocytes to KLH:Evidence for HLA-D region restriction, J. Immunol. 123:2250–2253.
Ross, G. N., Baroff, L. J., and Quismorio, F. P., 1975, Serratia arthritis in heroin users, J. Bone Joint Surg. 57A:1158–1160.
Sasazuki, T., Kaneoka, H., Nishimura, Y., Kaneoka, R., Hayama, M., and Ohkuni, H., 1980, An HLA- linked immune suppression gene in man, J. Exp. Med. 152:297s–313s.
Schmid, F. R., 1985, Principles of diagnosis and treatment of bone and joint infections, in:Arthritis and Allied Conditions ( D. J. McCarty, ed.), Lea & Febiger, Philadelphia, pp. 1627–1650.
Schurman, D. L., Mirra, J., Ding, A., and Nagel, D. A., 1977, Experimental E. coli arthritis in rabbits. A model of infectious and post-infectious inflammatory synovitis, J. Rheumatol. 4:118–127.
Schwab, J. H., Cromartie, W. J., Ohanian, S. H., and Craddock, J. G., 1967, Association of experimental chronic arthritis with the persistence of group A streptococcal cell walls in the articular tissue, J. Bacteriol. 94:1728–1735.
Schwartz, B. D., Luehrman, L. K., and Rodey, G. E., 1979, Public antigenic determinant on a family of HLA-B molecules, J. Clin. Invest. 64:938–994.
Seager, K., Bashir, H. V., Gelzy, A. F., Edmonds, J., and Tyndall, A., 1979, Evidence for a specific B27 associated cell surface marker on lymphocytes of patients with ankylosing spondylitis, Nature 277:68–70.
Shagrin, J. W., Frame, B., and Duncan, H., 1971, Polyarthritis in obese patients with intestinal bypass, Ann. Intern. Med. 75:377–380.
Sheagren, J. N., 1984, Staphylococcus areus: The persistent pathogen, N. Engl. J. Med.310:1368–1373,1437–1442.
Simpson, R. W., Smith, C., and Godzeski, C., 1984, Association of parvoviruses with rheumatoid arthritis of humans, Science 223:1425.
Small, C. B., Slater, L. N., Lowy, F. D., Small, R. D., Salvati, E. A., and Casey, J. I., 1984, Group B streptococcal arthritis in adults, Am. J. Med. 76:367–375.
Smialowicz, R. J., and Schwab, J. H., 1977, Processing of streptococcal cell walls by rat macrophages and human monocytes in vitro, Infect. Immun. 17:591–598.
Summers, G. D., and Jayson, M. I. V., 1980, Does Poncet’s disease exist? Rheumatol. Rehabil. 19:149–150.
Taurog, J. D., Leary, S. L., Cremer, M. A., Mahowald, M. L., Sandberg, G. P., and Manning, P. J., 1984, Infection with Mycoplasma pulmonis modulated adjuvant- and collagen-induced arthritis in Lewis rats, Arthritis Rheum. 27:943–946.
Urman, J. D., Zurier, R. B., and Rothfield, N. F., 1977, Reiter’s syndrome associated with Campylobacter infection, Ann. Intern. Med. 86:444–446.
Utsinger, P. D., 1980, Bypass disease: A bacterial antigen-antibody systemic immune complex disease, Arthritis Rheum. 23:758.
Van den Berg-Loonen, E. M., Dekker-Saeys, B. J., Meuwissen, S. G. M., Nijenhuis, L. E., and Engelfriet, C. R., 1977, Histocompatibility antigens and other genetic markers in ankylosing spondylitis and inflammatory bowel diseases, J. Immunogenet. 4:167–175.
van der Linden, S. M., Valkenburg, H. A., de Jongh, B. M., and Cats, A., 1984, The risk of developing ankylosing spondylitis in HLA-B27 positive individuals: A comparison of relatives of spondylitis patients with the general population, Arthritis Rheum. 27:241–249.
Waldvogel, F. A., Medoff, G., and Schwartz, M. N., 1970, Osteomyelitis: A review of clinical features, therapeutic considerations and unusual aspects, N. Engl. J. Med. 282:198–206, 260–266, 316–322.
Walker, L. C., Ahlin, T. D., Tung, K. S., and Williams, R. C., Jr., 1978, Circulating immune complexes in disseminated gonorrheal infection, Ann. Intern. Med. 89:28–33.
Wands, J. R., LaMont, J. T., Mann, E., and Isselbacher, K. J., 1976, Arthritis associated with intestinal bypass procedure for morbid obesity:Complement activation and characterization of circulating cryopro- teins, N. Engl. J. Med. 294:121–124.
Warren, R. E., and Brewerton, D. A., 1980, Faecal carriage of Klebsiella by patients with ankylosing spondylitis and rheumatoid arthritis, Ann. Rheum. Dis. 39:37–44.
Washburn, L. R., Cole, B. C., and Ward, J. R., 1982, Chronic arthritis of rabbits induced by mycoplasmas:III. Induction with non-viable Mycoplasma arthritidis antigens, Arthritis Rheum. 25:937–946.
Wehrbein, H. L., 1929, Gonococcus arthritis: A study of six hundred and ten cases, Surg. Gynecol. Obstet. 49:105–113.
Welsh, J., Avakian, H., Cowling, P., Ebringer, A., Wooley, P., Panayi, G., and Ebringer, R., 1980, Ankylosing spondylitis, HLA-B27 and Klebsiella. I. Cross-reactivity studies with rabbit antisera, Br. J. Exp. Pathol. 61:85–91.
Wilder, R. L., and Allen, J. B., 1984, The role of thymus-dependent lymphocytes in the pathogenesis of group A streptococcal cell wall-induced arthritis (SCWIA) in rats, Arthritis Rheum. 37:S36.
Wilder, R. L., Calandra, G. B., Garvin, A. J., Wright, K. D., and Hansen, C. T., 1982, Strain and sex variation in the susceptibility to streptococcal cell wall-induced polyarthritis in the rat, Arthritis Rheum. 25:1064–1072.
Wilder, R. L., Allen, J. B., Wahl, L. M., Calandra, G. B., and Wahl, S. M., 1983, The pathogenesis of group A streptococcal cell wall-induced polyarthritis in the rat, Arthritis Rheum. 26:1442–1451.
Willkens, R. F., Healey, L. A., and Decker, J. L., 1960, Acute infectious arthritis in the aged and chronically ill, Arch. Intern. Med. 106:334–364.
Woodrow, J. C., 1977, Histocompatibility antigens and rheumatic diseases, Semin. Arthritis Rheum. 6:257–276.
Wright, V., and Watkinson, G., 1966, Articular complications of ulcerative colitis, Am. J. Proctol. 17:107–115.
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Schmid, F.R. (1985). Infectious Agents in Rheumatic Diseases. In: Gupta, S., Talal, N. (eds) Immunology of Rheumatic Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2493-5_14
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