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Perspectives in the Use of Antiviral Agents for Prevention and Treatment of Respiratory Virus Infections

  • S. J. Sperber
  • F. G. Hayden
Chapter
Part of the Developments in Medical Virology book series (DIMV, volume 3)

Abstract

Respiratory viral infections are the most common infectious diseases of man and a major cause of morbidity and mortality globally. In developing countries respiratory viruses remain an important cause of childhood mortality (1). Acute respiratory diseases, which are frequently caused by viral infections, account for 20% of childhood mortality and in some parts of the world are the commonest cause of death in children (1). It is estimated that 2.2 million deaths occur throughout the world annually as a result of acute respiratory diseases. These diseases account for about 13% of all deaths in Africa, Central America and the developing countries of Asia, compared to 3% in North America (1). In developed countries certain viral infections continue to cause significant mortality in high-risk groups, particularly infants and the elderly. In the United States, influenza virus epidemics have been estimated to have been associated with over 10,000 excess deaths during 18 of the past 28 years (2).

Keywords

Respiratory Syncytial Virus Antiviral Agent Common Cold Respiratory Virus Respiratory Viral Infection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing 1988

Authors and Affiliations

  • S. J. Sperber
    • 1
  • F. G. Hayden
    • 1
  1. 1.Departments of Internal Medicine and PathologyUniversity of Virginia School of MedicineCharlottesvilleUSA

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