New and unusual infections in neutropenic patients

  • Stephen H. Zinner
Part of the Cancer Treatment and Research book series (CTAR, volume 79)


Medical practice lives with change. New advancements often bring unanticipated problems and new challenges. Thirty years ago the approach to fever in a granulocytopenic patient with acute leukemia was individualized, expectant, and based on microbiological documentation of the invading bacterial pathogen, with attribution of fever itself in large part to the underlying disease. The landmark paper of Schimpff et al. in 1971 [1] introduced the concept of empirical therapy with early administration of antibiotics directed against the most likely bacterial pathogens. This approach resulted in improved outcome from infectious episodes, and it has become the standard of therapy.


Clin Infect Neutropenic Patient Viridans Streptococcus Follow Bone Marrow Transplantation Peliosis Hepatis 
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Copyright information

© Kluwer Academic Publishers 1995

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  • Stephen H. Zinner

There are no affiliations available

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