The role and importance of distal embolization in complications arising during percutaneous interventions are now considered well established; however, this is a relatively new concept . Early in the evolution of interventional cardiology, distal embolization was not thought to be a significant problem [2,3]. Instead, the mechanism of dilatation was conceptualized as analogous to “stepping onto a layer of snow,” which was then compressed, with the procedure leading to larger lumen size without injuring the wall itself and without embolization.
Unable to display preview. Download preview PDF.
- 11.Bhatt DL, Topol EJ: Periprocedural myocardial infarction and emboli protection. In Textbook of Interventional Cardiology. Philadelphia: WB Saunders; 2003:251–266.Google Scholar
- 12.Frink RJ, Ostrach LH, Rooney PA, Rose J: Coronary thrombosis, ulcerated athersclerotic plaques and platelet/fibrin microemboli in patients dying with acute coronary disease: a large autopsy study. J Clin Invest 1990, 2:199–210.Google Scholar
- 15.Gibson CM, Cannon CP, Murphy SA, et al.: Relationship of TIMI myocardial perfusion grades, flow grades, frame count, and percutaneous coronary intervention to long-term outcomes after thrombolytic administration in acute myocardial infarction. Circulation 2002, 105:1909–1913.PubMedCrossRefGoogle Scholar
- 20.Bairn DS, Wahr D, George B, et al.: Randomized trial of a distal embolic protection device during percutaneous intervention of saphenous vein aorto-coronary bypass grafts. Circulation 2002, 105:1285–1290.Google Scholar
- 24.Yadav, J et al.: SAPPHIRE Study of Angioplasty with Distal Protection in Patients at High Risk for Endarterectomy, Late Breaking Clinical Trial, AHA 2002.Google Scholar