Pediatric Liver Transplantation
Thirty years after liver transplantation (LT) was first successfully performed in a young child, it remains the treatment of choice for children with end-stage liver disease, malignancy, and liver-based metabolic diseases. After initial technical challenges were overcome, survival became limited by rejection, infectious complications, and other complications of immunosuppression. Long-term patient and graft survival dramatically improved after the introduction of cyclosporine in 1980 and tacrolimus in 1989.
KeywordsPediatric surgery Liver disease Children Orthotopic liver transplantation EHPVO Meso-Rex bypass Split liver transplant Living donor liver transplant Operative techniques
Left Lobe Living Donor Freise (Humar) (MP4 392 mb)
Liver Intestine transplant pediatric recipient (MOV 3.10 gb)
- Maksoud-Filho JG, Goncalves MEP, Cardoso SR, Gibelli NEM, Tannuri U. Long-term follow-up of children with extrahepatic portal vein obstruction: impact of an endoscopic sclerotherapy program on bleeding episodes, hepatic function, hypersplenism and mortality. J Pediatr Surg. 2009;44:1877–83.CrossRefPubMedGoogle Scholar
- Martin SR, Atkison P, Anand R, Lindblad AS, SPLIT Research Group. Studies of Pediatric Liver Transplantation 2002: patient and graft survival and rejection in pediatric recipients of a first liver transplant in the United States and Canada. Pediatr Transplant. 2004;8:273–83.CrossRefPubMedGoogle Scholar