Macrophage Pattern Recognition Receptors in Immunity, Homeostasis and Self Tolerance

  • Subhankar Mukhopadhyay
  • Annette Plüddemann
  • Siamon Gordon
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 653)


Macrophages, a major component of innate immune defence, express a large repertoire of different classes of pattern recognition receptors and other surface antigens which determine the immunologic and homeostatic potential of these versatile cells. In the light of present knowledge of macrophage surface antigens, we discuss self versus nonself recognition, microbicidal effector functions and self tolerance in the innate immune system.


Scavenger Receptor Pattern Recognition Receptor Mannose Receptor Lectin Domain Macrophage Scavenger Receptor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Landes Bioscience and Springer Science+Business Media 2009

Authors and Affiliations

  • Subhankar Mukhopadhyay
    • 1
  • Annette Plüddemann
    • 1
  • Siamon Gordon
    • 1
  1. 1.Sir William Dunn School of PathologyOxfordUK

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