Wilms Tumor (nephroblastoma)
Wilms tumors are nephroblastomas arising in young children from nephrogenic rests, parts of the developing kidney that have failed to complete differentiation. Accordingly, the tumor mass consists of several components resembling tissue structures in the fetal kidney, such as blastema, mesenchymal stroma, and tubular structures. Most cases can be cured by a combination of chemotherapy and surgery.
KeywordsImprint Gene Gonadal Dysgenesis Uniparental Disomy Mesenchymal Stroma Frasier Syndrome
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