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Cisplatin Derivatives as Antiviral Agents

  • Michael R. Roner
  • Charles E. CarraherJr.
Chapter

The use of polymeric derivatives of cisplatin as antiviral drugs is reviewed. Some of these drugs inhibit a wide variety of both RNA and DNA viruses including those responsible for herpes, common colds, chickenpox, and smallpox. The desirability of polymeric drugs is described as is the mode(s) of action of cisplatin itself. A description of viruses and methods of combating viruses is presented. Included is a review of current antiviral agents as well as modes of action of these antiviral agents.

Keywords

Cisplatin cisplatin polymers herpes chickenpox smallpox cancer virus antivirals Balb 3T3 cells tilorone methotrexate diabetes 143 cells vero cells BS-C-1 cells L929 cells bioterrorism organotin polymers ampicillin norfloxacin antibacterial drugs 

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Copyright information

© Springer 2008

Authors and Affiliations

  • Michael R. Roner
    • 1
  • Charles E. CarraherJr.
    • 2
  1. 1.Department of BiologyUniversity of Texas at ArlingtonArlingtonUSA
  2. 2.Florida Center for Environmental StudiesPalm Beach GardensUSA

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