Advertisement

Synergistic Inhibition of Sars-Coronavirus Replication by Type I and Type II IFN

  • Eric C. Mossel
  • Bruno SainzJr.
  • Robert F. Garry
  • C. J. Peters
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 581)

Keywords

Severe Acute Respiratory Syndrome Synergistic Inhibition Antiviral State Severe Acute Respiratory Syndrome Coronavirus Lassa Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Haagmans, B. L., Kuiken, T., Martina, B. E., Fouchier, R. A., Rimmelzwaan, G. F., van Amerongen, G., van Riel, D., de Jong, T., Itamura, S., Chan, K. H., Tashiro, M., and Osterhaus, A. D., 2004, Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques, Nat. Med. 10:290-293CrossRefPubMedGoogle Scholar
  2. 2.
    Loutfy, M. R., Blatt, L. M., Siminovitch, K. A., Ward, S., Wolff, B., Lho, H., Pham, D. H., Deif, H., LaMere, E. A., Chang, M., Kain, K. C., Farcas, G. A., Ferguson, P., Latchford, M., Levy, G., Dennis, J. W., Lai, E. K., and Fish, E. N., 2003, Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study, JAMA 290:3222-3228CrossRefPubMedGoogle Scholar
  3. 3.
    Cinatl, J., Morgenstern, B., Bauer, G., Chandra, P., Rabenau, H., and Doerr, H. W., 2003, Treatment of SARS with human interferons, Lancet 362:293-294CrossRefPubMedGoogle Scholar
  4. 4.
    Hensley, L. E., Fritz, L. E., Jahrling, P. B., Karp, C. L., Huggins, J. W., and Geisbert, T. W., 2004, Interferon-beta 1a and SARS coronavirus replication, Emerg. Infect. Dis. 10:317-319PubMedGoogle Scholar
  5. 5.
    Scagnolari, C., Vicenzi, E., Bellomi, F., Stillitano, M. G., Pinna, D., Poli, G., Clementi, M., Dianzani, F., and Antonelli, G., 2004, Increased sensitivity of SARS-coronavirus to a combination of human type I and type II interferons, Antivir. Ther. 9:1003-1011PubMedGoogle Scholar
  6. 6.
    Spiegel, M., Pichlmair, A., Muhlberger, E., Haller, O., and Weber, F., 2004, The antiviral effect of interferon-beta against SARS-coronavirus is not mediated by MxA protein, J. Clin. Virol. 30:211-213PubMedGoogle Scholar
  7. 7.
    Stroher, U., DiCaro, A., Li, Y., Strong, J. E., Aoki, F., Plummer, F., Jones, S. M., and Feldmann, H., 2004, Severe acute respiratory syndrome-related coronavirus is inhibited by interferon- alpha, J. Infect. Dis. 189:1164-1167CrossRefPubMedGoogle Scholar
  8. 8.
    Asper, M., Sternsdorf, T., Hass, M., Drosten, C., Rhode, A., Schmitz, H., and Gunther, S., 2004, Inhibition of different Lassa virus strains by alpha and gamma interferons and comparison with a less pathogenic arenavirus, J. Virol. 78:3162-3169CrossRefPubMedGoogle Scholar
  9. 9.
    Czarniecki, C. W., Fennie, C. W., Powers, D. B., and Estell, D. A., 1984, Synergistic antiviral and antiproliferative activities of Escherichia coli-derived human alpha, beta, and gamma interferons, J. Virol. 49:490-496PubMedGoogle Scholar
  10. 10.
    Fleischmann, W. R., Jr., Georgiades, J. A., Osborne, L. C., and Johnson, H. M., 1979, Potentiation of interferon activity by mixed preparations of fibroblast and immune interferon, Infect. Immun. 26:248-253PubMedGoogle Scholar
  11. 11.
    Sainz, Jr., B., and Halford, W. P., 2002, Alpha/Beta interferon and gamma interferon synergize to inhibit the replication of herpes simplex virus type 1, J. Virol. 76:11541-11550CrossRefPubMedGoogle Scholar
  12. 12.
    Schwarz, L. A., Fleischmann, C. M., and Fleischmann, Jr., W. R., 1984, Potentiation of interferon's antiviral activity by the mutually synergistic interaction of MuIFN-alpha/beta and MuIFN-gamma, J. Biol. Response Mod. 3:608-612PubMedGoogle Scholar
  13. 13.
    Sainz, Jr., B., Mossel, E. C., Peters, C. J., and Garry, R. F., 2004, Interferon-beta and interferon-gamma synergistically inhibit the replication of severe acute respiratory syndrome-associated coronavirus (SARS-CoV), Virology 329:11-17CrossRefPubMedGoogle Scholar
  14. 14.
    Sainz, Jr., B., Lamarca, H. L., Garry, R. F., and Morris, C. A., 2005, Synergistic inhibition of human cytomegalovirus replication by interferon-alpha/beta and interferon-gamma, Virol. J. 2:14CrossRefPubMedGoogle Scholar
  15. 15.
    Akerstrom, S., Mousavi-Jazi, M., Klingstrom, J., Leijon, M., Lundkvist, A., and Mirazimi, A., 2005, Nitric oxide inhibits the replication cycle of severe acute respiratory syndrome coronavirus, J. Virol. 79:1966-1969CrossRefPubMedGoogle Scholar
  16. 16.
    Sekellick, M. J., Lowenthal, J. W., O'Neil, T. E., and Marcus, P. I., 1998, Chicken interferon types I and II enhance synergistically the antiviral state and nitric oxide secretion, J. Interferon Cytokine Res. 18:407-414CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Eric C. Mossel
    • 1
  • Bruno SainzJr.
    • 2
  • Robert F. Garry
    • 3
  • C. J. Peters
    • 4
  1. 1.Colorado State UniversityFort CollinsUSA
  2. 2.The Scripps Research InstituteLa JollaUSA
  3. 3.Tulane University Health Sciences CenterNew OrleansUSA
  4. 4.University of Texas Medical BranchGalvestonUSA

Personalised recommendations