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Use of a PRRSV Infectious Clone to Evaluate in Vitro Quasispecies Evolution

  • Susan K. Schommer
  • Steven B. Kleiboeker
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 581)

Keywords

Infectious Clone Respiratory Syndrome Virus Equine Arteritis Virus Master Sequence Increase Passage Number 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Meng, X.-J., 2000, Heterogeneity of porcine reproductive and respiratory syndrome virus: implications for current vaccine efficacy and future vaccine development, Vet. Microbiol. 74:309-329.CrossRefPubMedGoogle Scholar
  2. 2.
    Rowland, R. R., Steffen, M., Ackerman, T., and Benfield, D. A., 1999, The evolution of porcine reproductive and respiratory syndrome virus: quasispecies and emergence of a virus subpopulation during infection of pigs with VR-2332, Virology 259:262-266.CrossRefPubMedGoogle Scholar
  3. 3.
    Allende, R., Laegried, W. W., Kutish, G. F., Galeota, J. A., Will, R. W., and Osario, F. A., 2000, Porcine reproductive and respiratory syndrome virus: description of persistence in individual pigs upon experimental infection, J. Virol. 74:10834-10837.CrossRefPubMedGoogle Scholar
  4. 4.
    Chang, C. C., Yoon, K. J., Zimmerman, J. J., Harmon, K. M., Dixon, P. M., Dvorak, C. M. T., and Murtaugh, M. P., 2002, Evolution of porcine reproductive and respiratory syndrome virus during sequential passages in pigs, J. Virol. 76:4750-4763.CrossRefPubMedGoogle Scholar
  5. 5.
    Goldberg, T. L., Lowe, J. F., Milburn, S. M., and Firkins, L. D., 2003, Quasispecies variation of porcine reproductive and respiratory syndrome virus during natural infection, Virology. 317:197-207.CrossRefPubMedGoogle Scholar
  6. 6.
    de Vries, A. A., Chirnside, E. D., Horzinek, M. C., and Rottier, P. J., 1992, Structural proteins of equine arteritis virus, J. Virol. 66:6294-6303.PubMedGoogle Scholar
  7. 7.
    Allende, R., Lewis, T. L., Lu, Z., Rock, D. L., Kutish, G. F., Ali, A., Doster, A. R., and Osario, F. A., 1999, North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regions, J. Gen. Virol. 80:307-315.PubMedGoogle Scholar
  8. 8.
    Oleksiewicz, M. B., Botner, A., Toft, P., Normann, P., and Storgaard, T., 2001, Epitope mapping porcine reproductive and respiratory syndrome virus by phage display: the nsp2 fragment of the replicase polyprotein contains a cluster of B-cell epitopes, J. Virol. 75:3277-3290.CrossRefPubMedGoogle Scholar
  9. 9.
    Pirzadeh, B., and Dea, S., 1997, Monoclonal antibodies to the ORF5 product of porcine reproductive and respiratory syndrome virus define linear neutralizing determinants, J. Gen. Virol. 78:1867-1873.PubMedGoogle Scholar
  10. 10.
    Meng, X. J., Paul, P. S., Halbur, P. G., and Lum, M. A., 1995, Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the USA and Europe, Arch. Virol. 140:745-755.CrossRefPubMedGoogle Scholar
  11. 11.
    Gagnon, C. A., and Dea, S., 1998, Differentiation between porcine reproductive and respiratory syndrome virus isolates by restriction fragment length polymorphism of their ORFs 6 and 7 genes, Can. J. Vet. Res. 62:110-116.PubMedGoogle Scholar
  12. 12.
    Nielsen, H. S., Liu, G., Nielsen, J., Oleksiewicz, M. B., Botner, A., Storgaard, T., and Faaberg, K. S., 2003, Generation of an infectious clone of VR-2332, a highly virulent North American-type isolate of porcine reproductive and respiratory syndrome virus, J. Virol. 77:3702-3711.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Susan K. Schommer
    • 1
  • Steven B. Kleiboeker
    • 2
  1. 1.University of MissouriColumbiaUSA
  2. 2.University of MissouriColumbiaUSA

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