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Receptor-Independent Spread of a Neurotropic Murine Coronavirus MHV-JHMv in Mixed Neural Culture

  • Keiko Nakagaki
  • Kazuhide Nakagaki
  • Fumihiro Taguchi
Conference paper
  • 974 Downloads
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 581)

Keywords

Neural Cell Syncytium Formation Mouse Hepatitis Virus Spike Protein Single Amino Acid Mutation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Gallagher, T. M., and Buchmeier, M. J., 2001, Coronavirus spike proteins in viral entry and pathogenesis, Virology 279:371–374.CrossRefPubMedGoogle Scholar
  2. 2.
    Hirayama, M., Silberberg, D. H., Lisak, R. P., and Pleasure, D., 1983, Long-term culture of oligodendrocytes isolated from rat corps callosum by percoll density gradient. Lysis by polyclonal antigalactocerebroside serum, J. Neuropathol. Exp. Neurol. 42:16–28.CrossRefPubMedGoogle Scholar
  3. 3.
    Kubo, H., Takase, Y-S., and Taguchi, F., 1993, Neutralization and fusion inhibition activities of monoclonal antibodies specific for S1 subunit of the spike protein of neurovirulent murine coronavirus HMV cl-2 variant, J. Gen. Virol. 74:1421–1425.CrossRefPubMedGoogle Scholar
  4. 4.
    Ramarkrishna, C., Bergmann, C. C., Holmes, K. V., and Stohlman, S., 2004, Expression of the mouse hepatitis virus receptor by central nervous system microglia, J. Virol. 78:7828–7832.CrossRefGoogle Scholar
  5. 5.
    Saeki, K., Ohtsuka, N., and Taguchi, F., 1997, Identification of spike protein residues of murine coronavirus responsible for receptor-binding activity by use of soluble receptor-resistant mutants, J. Virol. 71:9024–9031.PubMedGoogle Scholar
  6. 6.
    Williams, R. K., Jiang, G. S., Snyder, S. W., Frana, M. F., and Holmes, K. V., 1990, Purification of the 110-kilodalton glycoprotein receptor for mouse hepatitis virus (MHV)-A59 from mouse liver and identification of a nonfunctional, homologous protein in MHV-resistant SJL/J mice, J. Virol. 64:3817–3823.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Keiko Nakagaki
    • 1
  • Kazuhide Nakagaki
    • 2
  • Fumihiro Taguchi
    • 3
  1. 1.National Institute of Infectious DiseasesJapan
  2. 2.Nippon Veterinary and Animal Science UniversityJapan
  3. 3.National Institute of Infectious DiseasesJapan

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