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B Cells Carrying Antigen Receptors Against Microbes as Tools for Vaccine Discovery and Design

  • Deepika Bhullar
  • David NemazeeEmail author
Chapter
Part of the Current Topics in Microbiology and Immunology book series

Abstract

Can basic science improve the art of vaccinology? Here, we review efforts to understand immune responses with the aim to improve vaccine design and, eventually, to predict the efficacy of human vaccine candidates using the tools of transformed B cells and targeted transgenic mice carrying B cells with antigen receptors specific for microbes of interest.

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Immunology and MicrobiologyThe Scripps Research InstituteLa JollaUSA

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