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Nosocomial Infections in Patients Hospitalized with Respiratory Syncytial Virus: A Practice Review

  • August Wrotek
  • Małgorzata Czajkowska
  • Teresa JackowskaEmail author
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1271)

Abstract

Viral testing is not always recommended in children with bronchiolitis due to doubts concerning its prognostic use. In this retrospective study, we investigated how the RSV testing would influence the frequency of nosocomial infections (NI). The files of 305 children, hospitalized due to the respiratory syncytial virus (RSV) infection in the period 2010–2014, were reviewed in the study. We found ten cases of NI. The RSV preventive measures did not vary in the consecutive years investigated, but the number of viral tests substantially varied. In 2010, 2012, and 2014, when ca. 2 tests per RSV(+) patient were performed, the risk of NI per patient was 1.3%, while in 2011 and 2013, when the RSV testing was less frequent, the accumulated risk per patient was 5.2%. There was a strong adverse relationship between the number of tests performed and the number of NI (rho = −0.975). The children with NI, when compared to those without NI, required a longer hospital stay, generating higher hospital costs regarding treatment, productivity loss, and indirect costs. The expenditure for RSV testing in the years of a low NI risk was higher than that in the high-risk years. Conversely, the expenditure related to NI management was lower in the years of a low NI risk. Each euro spent on RSV testing saved over 26 € from the NI management expenditure. We conclude that RSV testing is needed in the hospital setting to isolate the infected children and to prevent nosocomial RSV spread. This strategy is health advantageous and requires less resources than NI treatment.

Keywords

Bronchiolitis Community-acquired disease Health costs Healthcare Nosocomial infection Respiratory syncytial virus Treatment efficacy 

Notes

Acknowledgments

This study was supported by CMKP Grant 501-1-020-19-19.

Conflicts of Interest

The authors declare no conflict of interest in relation to this article.

Ethical Approval

This retrospective review of medical files does not contain any experiments with human participants or animals performed by any of the authors.

Informed Consent

There are no identifiable participants included in this retrospective article. Therefore, there was no requirement to obtain individual informed consent.

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • August Wrotek
    • 1
    • 2
  • Małgorzata Czajkowska
    • 1
    • 2
  • Teresa Jackowska
    • 1
    • 2
    Email author
  1. 1.Department of PediatricsCenter of Postgraduate Medical EducationWarsawPoland
  2. 2.Department of PediatricsBielanski HospitalWarsawPoland

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