Thrombotic Microangiopathy Syndrome in the ICU

  • S. Samy Modeliar
  • M. Monge
  • M. Slama
Conference paper
Part of the Yearbook of Intensive Care and Emergency Medicine book series (YEARBOOK, volume 2006)


Major studies designed to improve our understanding of the pathophysiology of TMA have been conducted over recent years. This improved knowledge opens up new perspectives for more targeted treatment. However, until these innovative treatments become available, early diagnosis of these diseases is essential in order to rapidly initiate specific treatment, as the interval between diagnosis and initiation of plasma exchange is a decisive element in the prognosis of TTP. Treatment must not be stopped too early or too rapidly and must take into account the various associated factors, especially the presence of infection.


Intensive Care Unit Human Immunodeficiency Virus Plasma Exchange Disseminate Intravascular Coagulation Hemolytic Uremic Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • S. Samy Modeliar
    • 1
  • M. Monge
    • 2
  • M. Slama
    • 3
  1. 1.Nephrology Department, Intensive Care UnitCHU Amiens — Hôpital SudAmiensFrance
  2. 2.Nephrology Internal Medicine DepartmentCHU Amiens — Hôpital SudAmiensFrance
  3. 3.Nephrology Internal Medicine Department, Intensive Care UnitCHU Amiens — Hôpital SudAmiensFrance

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