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Impact of Amnion-Derived Mesenchymal Stem Cells on Wound Healing

  • Alexandru-Cristian TucaEmail author
  • Ingrid Lang-Olip
Part of the Recent Clinical Techniques, Results, and Research in Wounds book series


To date tremendous effort has been made toward a better insight and understanding of the mechanisms of mesenchymal stem cells (MSCs) through which they can promote wound healing and cell regeneration. Although MSCs can be derived from a large number of tissues, neonatal tissues like the amnion get more and more into the focus of research interest as they are noninvasive candidates for cell isolation. Furthermore, current literature suggests their superior proliferation and differentiation abilities compared to MSCs originating from adult tissues such as bone marrow or adipose tissue. In this chapter, we present the to date known therapeutic capacities and underlying mechanisms of MSCs on tissue regeneration and wound healing with special focus on human amnion-derived mesenchymal stem cells (hAMSCs).


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Research Unit for Tissue Regeneration, Repair, and Reconstruction, Division of Plastic, Aesthetic and Reconstructive Surgery, Department of SurgeryMedical University of GrazGrazAustria
  2. 2.Department of Cell Biology, Histology and EmbryologyGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of GrazGrazAustria

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