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An Approach to Keloid Reconstruction with Dermal Substitute and Epidermal Skin Grafting

  • Tommaso Agostini
  • Christian Pascone
  • Raffaella Perello
  • Antonio Di Lonardo
Part of the Recent Clinical Techniques, Results, and Research in Wounds book series


Keloids represent a challenging topic for reconstructive surgeons. Surgical debulking is the main treatment for these lesions, although recurrence rates are reported to be 45–100%. Here, we present a staged reconstructive approach through a dermal regeneration substrate and epidermal grafting in order to minimize recurrence and donor site morbidity. All keloids were excised down to healthy tissue. A bilaminar dermal regeneration template was used to reconstruction, with the silicone lamina oriented superficially. The second step of reconstruction was delayed for at least 21 days to allow for neodermal ingrowth. Once the protective lamina was removed, an epidermal skin graft was applied to the neodermis with nonocclusive dressing. This combined approach limits scar contracture facilitating tension-free wound healing with a consequent lower rate of recurrences.


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Tommaso Agostini
    • 1
  • Christian Pascone
    • 1
  • Raffaella Perello
    • 1
  • Antonio Di Lonardo
    • 1
  1. 1.Department of Plastic and Reconstructive SurgeryClinica San PaoloPistoiaItaly

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