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Strategic Actionable Net-Centric Biological Defense System

  • S. Kornguth
Conference paper
  • 642 Downloads
Part of the NATO Security through Science Series book series (NAPS)

Abstract

Technologies required for strategic actionable net-centric biological defense systems consist of : 1) multiplexed multi-array sensors for threat agents and for signatures of the host response to infection; 2) novel vaccines and restricted access antivirals/bacterials to reduce emergence of drug resistant strains pre- and post-event; 3) telemedicine capabilities to deliver post-event care to 20,000 victims of a biological strike; and 4) communication systems with intelligent software for resource allocation and redundant pathways that survive catastrophic attack. The integrated system must detect all threat agents with minimal false positive/negative events, a seamless integrated broad-band communications capability that enables conversion of data to actionable information, and novel pre- and post-event treatments. The development of multiplexed multi-array sensors, appropriate vaccines and antibiotics, and integrated communication capabilities are critical to sustaining normal health, commerce, and international activities.

Keywords

Severe Acute Respiratory Syndrome Anthrax Toxin West Nile Fever Emergent Disease Threat Agent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Lessons from the Anthrax Attacks: Implications for U.S. Bioterrorism Preparedness. CSIS Funded by the Defense Threat Reduction Agency of the Department of Defense. David Heyman investigator. March 2004.Google Scholar
  2. 2.
    Maynard, J.A., Maassen, C.B.M., Leppla, S.H., Brasky, K., Patterson, J.L., Iverson, B.L., and Georgiou, G., “Protection against Anthrax Toxin by Recombinant Antibody Fragments Correlates with Antigen Affinity,” Nature Biotechnology, vol. 20, pp. 597–601, June 2002.CrossRefGoogle Scholar

Copyright information

© Springer 2005

Authors and Affiliations

  • S. Kornguth
    • 1
  1. 1.Countermeasures to Biological and Chemical Threats Institute for Advanced TechnologyUniversity of Texas at AustinUSA

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