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Free Radicals and Medicine

  • H.M. Swartz
  • R. P. Mason
  • N. Hogg
  • B. Kalyanaraman
  • T. Sarna
  • P.M. Plonka
  • M. Zareb
  • P. L. Gutierrez
  • L. J. Berliner
Chapter
  • 1.2k Downloads
Part of the Biological Magnetic Resonance book series (BIMR, volume 23)

Abstract

EPR has been employed in attempts to understand the basis of specific pathophysiologies in which free radicals have a postulated role. Examples described include pulmonary free radical damage, free radicals and sickle cell disease, free radicals in amyotrophic lateral sclerosis, melanin and free radicals and the potential role of oxidative stress in the induction of cancer. The final section of the chapter describes the use of NMR as the spectroscopic measure of spin-trapped radicals, after they have reacted further to form diamagnetic species.

Keywords

Electron Paramagnetic Resonance Amyotrophic Lateral Sclerosis Retinal Pigment Epithelium Sickle Cell Disease Electron Paramagnetic Resonance Spectrum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  • H.M. Swartz
    • 1
  • R. P. Mason
    • 2
  • N. Hogg
    • 3
  • B. Kalyanaraman
    • 3
  • T. Sarna
    • 4
  • P.M. Plonka
    • 4
  • M. Zareb
    • 4
  • P. L. Gutierrez
    • 5
  • L. J. Berliner
    • 6
  1. 1.Dartmouth Medical SchoolHanoverUSA
  2. 2.NIH/NIEHSResearch Triangle ParkUSA
  3. 3.Medical College of WisconsinMilwaukeeUSA
  4. 4.Jagiellonian UniversityKrakowPoland
  5. 5.Greenebaum Cancer CenterUniversity of Maryland Medical SchoolBaltimoreUSA
  6. 6.University of DenverDenverUSA

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