Lipid Peroxidation in Patients with Diseases Known to Affect Trace Element Status

  • Mariana Vlad
  • P. J. Porr
  • G. Uza
  • Maria Zirbo


Serum Zinc Serum Copper Experimental Atherosclerosis Serum Lipid Peroxide Free Radical Injury 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Andrews, G.S., 1979, Studies of plasma zinc, copper, caeruloplasmin, and growth hormone. With special reference to carcinoma of the bronchus, J. of Clin. Pathol.32:325–333.CrossRefGoogle Scholar
  2. Bayer, W., 1982, in Mineralstoffwechsel und Abwehrsystem, (Schmidt, K. and Bayer, W. eds.), Verl. f. Medizin Dr. Ewald Fischer, Heidelberg, 17–32.Google Scholar
  3. Burke, J.P. and Fenton, M.R., 1985, Effect of a zinc-deficient diet on lipid peroxidation in liver and tumor subcellular membranes (42083), Proc. Soc. Exp. Biol. Med.179:187–191.CrossRefGoogle Scholar
  4. Diaz, M.N., Frei, B., Vita, J.A., and Keaney, J.F., 1997, Mechanisms of disease: Antioxidants and atherosclerotic heart disease, N. Engl J. Med.337(6):408–416.CrossRefGoogle Scholar
  5. Gaziano, L.M. and Hennekes, Ch.H., 1996, Update on dietary antioxidants and cancer, Path. Biol.44(1):42–45.Google Scholar
  6. Gey, K.F., 1993, Prospects for the prevention of free radical disease, regarding cancer and cardiovascular disease, Br. Med. Bull.49(3):679–699.CrossRefGoogle Scholar
  7. Günzler, W.A., Kremers, H., and Flohe, L., 1974, Z. Klin. Chem. Klin. Biochem.12:444–448.PubMedGoogle Scholar
  8. Klevay, L.M., 1980, Interaction of copper and zinc in cardiovascular disease, Ann. N. Y. Acad. Sci., 355:140–151CrossRefGoogle Scholar
  9. Kok, F.J., Van Duijn, C.M., Hofman, A., Van Der Voet, G.B., De Wolff, F.A., Paays, C.H.Ch., and Valkenburg, H.A., 1988, Serum copper and zinc and the risk of death from cancer and cardiovascular disease, Am. J. of Epidemiol.128(2):352–359.CrossRefGoogle Scholar
  10. Manta, I., Cucuianu, M., Benga, G., and Hodarnau, A., 1976, Metode biochimice in laboratorul clinic, Cluj-Napoca, Romania, Ed. Dacia.Google Scholar
  11. Mayne, S.T., 1996, Beta-carotene, carotenoids, and disease prevention in humans, FASEB J.10:690–701.CrossRefGoogle Scholar
  12. Pietrzik, K., 1996, Antioxidant vitamins, cancer, and cardiovascular disease, N. Engl. J. Med.335(14), 3, 1065–1069.Google Scholar
  13. Prasad, A.S., 1983, Clinical, biochemical and nutritional spectrum of zinc deficiency in human subjects: an update, Nutr. Rev.41:197–208.CrossRefGoogle Scholar
  14. Reunanen, A., Knekt, P., Marniemi, J., Maki, J., Maatela, J., and Aromaa, A., 1996, Serum calcium, magnesium, copper and zinc and risk of cardiovascular death, Eur. J. of Clin. Nutr.50:431–437.Google Scholar
  15. Savlov, E.D., Strain, W.H., and Huegin, F., 1962, Radiozinc studies in experimental wound healing, J. of Surgical Res.2:209–212.CrossRefGoogle Scholar
  16. Schrauzer, G.N., 1987, Trace elements in diagnosis and therapy. A review, Trace Element Analytical Chemistry in Medicine and Biology, 4, Schramel, P. and Bratter, P., eds, Walter de Gruyter, Berlin, NY.Google Scholar
  17. Tamas, V. and Neamtu, G., 1986, Pigmenti carotenoidici si metaboliti—Chimie si biochimie, Ed. Ceres, Bucuresti, vol. I.Google Scholar
  18. Uza, G. and Vlaicu, R., 1989, Serum zinc and copper in patients with atheroclerosis and trombangitis obliterans. Biol. Trace Elem. Res.2:197–206.CrossRefGoogle Scholar
  19. Vlad, M., Bordas, E., Tomus, R., Sava, D., and Farcas, E., 1993, Effect of copper sulfate on experimental atherosclerosis, Biol. Tr. Elem. Res.38:47–54.CrossRefGoogle Scholar
  20. Vlad, M., Caseanu, E., Uza, G., and Petrescu, M., 1994, Concentration of copper, zinc, chromium, iron, and nickel in the abdominal aorta of patients deceased with coronary heart disease, J. Tr. Elem. Electrolytes Health Dis., 8(2):111–114.Google Scholar
  21. Vlad, M., Uza, G., Zirbo, M., and Olteanu, Doina, 1995, Free radicals, ceruloplasmin, and copper concentration in serum and aortic tissue in experimental atherosclerosis, Supplement to Nutrition11(5):588–591.Google Scholar
  22. Wolff, S.P., 1993, Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the etiology of diabetes mellitus and complications, Br. Med. Bull.49(3):642–652.CrossRefGoogle Scholar
  23. Yagi, K., 1976, A simple fluorometric assay for lipoperoxide in blood plasma, Biochem. Med., 15:212–216.CrossRefGoogle Scholar

Copyright information

© Kluwer Academic Publishers 2002

Authors and Affiliations

  • Mariana Vlad
    • 1
  • P. J. Porr
    • 2
  • G. Uza
    • 3
  • Maria Zirbo
    • 4
  1. 1.Institute of Public HealthCluj NapocaRomania
  2. 2.3-rd Medical ClinicCluj NapocaRomania
  3. 3.Departmental Polyclinic IICluj NapocaRomania
  4. 4.University of Medicine and PharmacyCluj NapocaRomania

Personalised recommendations