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Nanotechnology: The Future for Cancer Treatment

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Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach

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Abstract

Nanotechnology, which is defined as the science behind the structures within the size range of 1–100 nm, potentially holds the key to treat several chronic diseases such as cardiovascular diseases, respiratory diseases and cancer. Nanoscale structures can provide promising tools for various applications in nanomedicine including those in drug delivery of therapeutics and imaging. Present-day cancer treatments suffer from severe side effects and lack specificity, thus affecting healthy cells. Nanoparticles, however, can preferentially accumulate only at the tumour site or can be targeted to cancer cells by surface functionalization using ligands. A major advantage of nanoparticles lies in the scope of surface modification and encapsulation of poorly soluble anticancer drug. This translates into higher therapeutic efficacy and lower toxicity for nanoparticle therapeutics. Thus, nanoparticles offer myriad potential in medical science. This chapter highlights various types of nanoparticles and targeting moieties that have potential to serve as drug carriers that can selectively target tumour cells.

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Acknowledgements

Y Patil-Sen would like to thank the Daphne Jackson Trust for the fellowship which provided an opportunity for her to return to research after a career break. The fellowship is jointly funded by the Royal Society of Chemistry and the University of Central Lancashire, UK.

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Authors and Affiliations

  1. School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, UK

    Yogita Patil-Sen

  2. Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Würzburg, Germany

    Ashwin Narain

  3. Department of Biotechnology, National Institute of Technology, Warangal, TS, India

    Simran Asawa & Tanvi Tavarna

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  1. Yogita Patil-Sen
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  2. Ashwin Narain
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  3. Simran Asawa
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  4. Tanvi Tavarna
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Correspondence to Yogita Patil-Sen .

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  1. Integrated Biophysics and Structural Biology Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Homi Bhabha National Institute, Navi Mumbai, Maharashtra, India

    Kakoli Bose

  2. Comparative Oncology Program and Small Animal Imaging Facility, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Homi Bhabha National Institute, Navi Mumbai, Maharashtra, India

    Pradip Chaudhari

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Patil-Sen, Y., Narain, A., Asawa, S., Tavarna, T. (2019). Nanotechnology: The Future for Cancer Treatment. In: Bose, K., Chaudhari, P. (eds) Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach. Springer, Singapore. https://doi.org/10.1007/978-981-32-9816-3_16

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