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Development of Neuroimaging-Based Biomarkers in Psychiatry

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Frontiers in Psychiatry

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1192))

Abstract

This chapter presents an overview of accumulating neuroimaging data with emphasis on translational potential. The subject will be described in the context of three disease states, i.e., schizophrenia, bipolar disorder, and major depressive disorder, and for three clinical goals, i.e., disease risk assessment, subtyping, and treatment decision.

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Abbreviations

AD:

Alzheimer’s disease

ADHD:

Attention deficit hyperactivity disorder

ACC:

Anterior cingulate cortex

BD:

Bipolar disorder

BOLD:

Blood oxygenation level dependent

CS:

Chronic schizophrenia

CT:

Computerized tomography

DALYs:

Disability-adjusted life years

DSM:

Diagnostics and Statistics Manual

DMN:

Default mode network

DLPFC:

Dorsolateral prefrontal cortex

DTI:

Diffusion tensor imaging

EPI:

Echo-planar imaging

FA:

Fractional anisotropy

FCS:

Functional connectivity strength

FES:

First episode schizophrenia

fMRI:

Functional magnetic resonance imaging

ICD:

International Classification of Diseases

MCI:

Mild cognitive impairment

MRI:

Magnetic resonance imaging

MDD:

Major depression disorder

mPFC:

Medial prefrontal cortex

NCD:

Neurocognitive disorder

OCD:

Obsessive-compulsive disorder

P4:

Predictive, preventative, personalized, and participatory

PET:

Positron emission tomography

RDoC:

Research domain criteria

SAD:

Social anxiety disorder

SZ:

Schizophrenia

SPECT:

Single-photon emission computed tomography

VBM:

Voxel-based morphometry

YLDs:

Years lived with disability

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  1. Psychology Program, Faculty of Arts and Social Sciences, International University of Sarajevo, Hrasnička cesta br. 15, 71210, Sarajevo, Bosnia and Herzegovina

    Orkun Aydin & Pinar Unal Aydin

  2. Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, International University of Sarajevo, Hrasnička cesta br. 15, 71210, Sarajevo, Bosnia and Herzegovina

    Ayla Arslan

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    Yong-Ku Kim

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Aydin, O., Unal Aydin, P., Arslan, A. (2019). Development of Neuroimaging-Based Biomarkers in Psychiatry. In: Kim, YK. (eds) Frontiers in Psychiatry. Advances in Experimental Medicine and Biology, vol 1192. Springer, Singapore. https://doi.org/10.1007/978-981-32-9721-0_9

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