Abstract
The sequence of diabetic sensory neuropathy, ulcer, infection, gangrene, and amputation generally captures more attention in practice as well as in literature. However, there has to be a component of motor neuropathy without which ulcers and its consequences to gangrene occur in substantial number than neuropathy alone. It is also now accepted that motor neuropathy can even precede diabetic sensory neuropathy. It means that motor neuropathic abnormalities also would be high in prevalence by which time the sensory neuropathic disturbances catch up known to be frequent. The first issue therefore is to recognize the concurrence of these two and its consequences. The affliction of motor component neuropathy of the hands in diabetes is least understood. Its detailed review with lower limb motor neuropathies will enhance its understanding of the clinicians.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Notes
- 1.
From surgical anatomy point of view, the flexor hallucis longus tendon is in close proximity of first metatarsal head where most ulcers in diabetic foot occur and the infection spreads along the flexor hallucis longus tendon all the way up in the calf. Hence the entire flexor hallucis longus tendon has to be traced back in such cases and excised till one comes across a viable tendon portion.
- 2.
Once the sensory neuropathy appears with, before or after the motor neuropathy, the feet become insensate and the person keeps walking even when an ulcer is formed since there is no pain. The ulcer then widens and deepens, serves as an entry point for infection and the subsequent complications. Most neuropathies in India and other less developed countries in South East Asia are sensory which thus adds to the burden of diabetic foot infections. Most ulcers begin small and should be taken care of, then the amputation rates will drastically come down (see the additional reading for all other details mentioned in other chapters).
References
Dyck PJ, Engelstad JN, Norell J, Dyck PJ. Microvasculitis in nondiabetic lumbosacral radiculoplexus neuropathy (LSRPN): similarity to the diabetic variety (DLSRPN). J Neuropathol Exp Neurol. 2000;59:525–38. PMID 10850865.
Dyck PJ, Norell JE, Dyck PJ. Methylprednisolone may improve lumbosacral radiculoplexus neuropathy. Can J Neurol Sci. 2001a;28(3):224–7. PMID 11513340.
Raff MC, Sangalang V, Asbury AK. Ischemic mononeuropathy multiplex associated with diabetes mellitus. Arch Neurol. 1968;18:487–99. PMID 5647941.
Dyck PJ, Norell JE, Dyck PJ. Microvasculitis and ischemia in diabetic lumbosacral radiculoplexus neuropathy. Neurology. 1999;53:2113–21. PMID 10599791.
Said G, Goulon-Goeau C, Lacroix C, Moulonguet A. Nerve biopsy findings in different patterns of proximal diabetic neuropathy. Ann Neurol. 1994;35:559–69. PMID 8179302.
Krendel DA, Castigan DA, Hopkins LC. Successful treatment of neuropathies in patients with diabetes mellitus. Arch Neurol. 1995;52:1053–61. PMID 7487556.
Kelkar P, Masood M, Parry GJ. Distinctive pathological finding in proximal diabetic neuropathy. Neurology. 2000;55:83–8. PMID 10891910.
Benatar M, Chapman KM, Rutkove SB. Repetitive nerve stimulation for the evaluation of peripheral nerve hyperexcitability. J Neurol Sci. 2004;221(1):47–52.
Harrison TB, Benatar M. Accuracy of repetitive nerve stimulation for diagnosis of the cramp–fasciculation syndrome. Muscle Nerve. 2007;35(6):776–80.
Smith LL, Burnet SP, McNeil JD. Musculoskeletal manifestations of diabetes mellitus. Br J Sports Med. 2003;37:30. -5. 41.
Sander HW, Chokroverty S. Diabetic amyotrophy: current concepts. Semin Neurol. 1996;16:173–8.
Subramony SH, Wilbourn AJ. Diabetic proximal neuropathy: clinical and electromyographic studies. J Neurol Sci. 1982;53:293–304. PMID 7057213.
Said G, Elgrably F, Lacroix C, et al. Painful proximal diabetic neuropathy: inflammatory nerve lesions and spontaneous favorable outcome. Ann Neurol. 1997;41:762–70. PMID 9189037.
Dyck PJ, Norell JE, Dyck PJ. Non-diabetic lumbosacral radiculoplexus neuropathy. Natural history, outcome and comparison with the diabetic variety. Brain. 2001b;124:1197–207. PMID 11353735.
https://www.diabetes.co.uk/diabetes-complications/stiff-hand-syndrome.html.
Arkkila PE, Gautier JF. Musculoskeletal disorders in diabetes mellitus: an update. Best Pract Res Clin Rheumatol. 2003;17:945–70.
Cagliero E, Apruzzese W, Perlmutter GS, Nathan DM. Musculoskeletal disorders of the hand and shoulder in patients with diabetes mellitus. Am J Med. 2002;112:487–90.
Bland JD. Carpal tunnel syndrome. BMJ. 2007;335:343–6.
Piazzini DB, Aprile I, Ferrara PE, Bertolini C, Tonali P, Maggi L, et al. A systematic review of conservative treatment of carpal tunnel syndrome. Clin Rehabil. 2007;21:299–314.
Makepeace A, Davis WA, Bruce DG, Davis TM. Incidence and determinants of carpal tunnel decompression surgery in type 2 diabetes: the Fremantle diabetes study. Diabetes Care. 2008;31:498–500.
Chiu H-Y, Hsu H-Y, Kuo L-C, Su F-C, Yu H-I, et al. How the impact of median neuropathy on sensorimotor control capability of hands for diabetes: an achievable assessment from functional perspectives. PLoS One. 2014;9(4):e94452. https://doi.org/10.1371/journal.pone.0094452.
Cederlunda RI, Thomsenb N, Thrainsdottirc S, et al. Hand disorders, hand function, and activities of daily living in elderly men with type 2 diabetes. J Diabetes Complicat. 2009;23:32–9.
Tiffin J, Asher EJ. The Purdue pegboard: norms and studies of reliability and validity. J Appl Psychol. 1948;32:234.
Horng YS, Lin MC, Feng CT, et al. Responsiveness of the Michigan hand outcomes questionnaire and the disabilities of the arm, shoulder, and hand questionnaire in patients with hand injury. J Hand Surg. 2010;35:430–6.22.
Boyer J, Earp J. The development of an instrument for assessing the quality of life of people with diabetes: diabetes-39. Med Care. 1997;35:440–53.
Huang IC, Hwang CC, Wu MY, et al. Diabetes-specific or generic measures for health-related quality of life? Evidence from psychometric validation of the D-39 and SF-36. Value Health. 2008;11:450–61.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Kelkar, S. (2020). Motor Neuropathy and Diabetic Hand Syndrome. In: Diabetic Neuropathy and Clinical Practice. Springer, Singapore. https://doi.org/10.1007/978-981-15-2417-2_10
Download citation
DOI: https://doi.org/10.1007/978-981-15-2417-2_10
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-15-2416-5
Online ISBN: 978-981-15-2417-2
eBook Packages: MedicineMedicine (R0)