Skip to main content

Biomedical Applications of Zinc Oxide Nanoparticles Synthesized Using Eco-friendly Method

  • Chapter
  • First Online:
Nanoparticles and their Biomedical Applications

Abstract

Nanotechnology is an emerging area of research and plays a vital role in various fields of application. Consequently, it mainly focused on synthesis of nanoparticles using novel approaches. Among this, synthesis of zinc oxide using biological method plays a unique role in research, such as cost-effective and environment-friendly method. In this review paper, we mainly focused on synthesis of zinc oxide nanoparticles using biological methods such as plant-mediated, bacterial-mediated, fungal-mediated, and algal-mediated method. These biological materials are enriched with biomolecules, and they play a major role in reduction of metals. Based on this, bioreduction capacity of various biological materials used to synthesize zinc oxide nanoparticles under different conditions is also provided in this review. Various instrumental techniques such as Fourier transform infrared (FT-IR), scanning electron microscopy (SEM), and X-ray diffraction (XRD) are used to characterize the size and functional group present in the nanoparticles, and some other biological techniques are also used to identify the effectiveness of novel-mediated zinc oxide nanoparticles. Finally, this review provides enough detail about the biological-mediated zinc oxide nanoparticles and its functional groups, and biological application; it helps researcher to identify previous results of the study and helps to pave new way for research.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Abinaya M, Vaseeharan B, Divya M, Sharmili A, Govindarajan M, Alharbi NS, Kadaikunnan S, Khaled JM, Benelli G (2018) Technical note bacterial exopolysaccharide (EPS)-coated ZnO nanoparticles showed high antibiofilm activity and larvicidal toxicity against malaria and Zika virus vectors. J Trace Elem Med Biol 45:93–103

    Article  CAS  PubMed  Google Scholar 

  • Ahmed S, Annu, Chaudhry SA, Ikram S (2017) Biogenic synthesis of ZnO nanoparticles using plant extracts and microbes: a prospect towards green chemistry. J Photochem Photobiol B: Biology 166:272–284

    Article  CAS  PubMed  Google Scholar 

  • Anbuvannan M, Ramesh M, Viruthagiri G, Shanmugam N, Kannadasan N (2015) Synthesis, characterization and photocatalytic activity of ZnO nanoparticles prepared by biological method. Spectrochim Acta A Mol Biomol Spectrosc 143:304–308

    Article  CAS  PubMed  Google Scholar 

  • Anbuvannana M, Ramesh M, Viruthagiri G, Shanmugam N, Kannadasan N (2015) Synthesis, characterization and photocatalytic activity of ZnO nanoparticles prepared by biological method. Mol Biomol Spectrosc 143:304–308

    Article  CAS  Google Scholar 

  • Aruna ST, Mukasyan AS (2008) Combustion synthesis and nanomaterials. Curr Opinion Solid State Mater Sci 12:44

    Article  CAS  Google Scholar 

  • Asmathunisha N, Kathiresan K (2013) A review on biosynthesis of nanoparticles by marine organisms. Colloids Surf B: Bionterfaces 103:283–287

    Article  CAS  Google Scholar 

  • Azizi S, Ahmad MB, Namvar F, Mohamad R (2014) Green biosynthesis and characterization of zinc oxide nanoparticles using brown marine macroalga Sargassum muticum aqueous extract. Mater Lett 116:275–277

    Article  CAS  Google Scholar 

  • Cauerhff A, Castro GR (2013) Bionanoparticles, a green nanochemistry approach. Electron J Biotechnol 16(3)

    Google Scholar 

  • Chandrasekaran R, Gnanasekar S, Seetharaman P, Keppanan R, Arockiaswamy W, Sivaperumal S (2016) Formulation of Carica papaya latex-functionalized silve rnanoparticles for its improved antibacterial and anticancer applications. J Mol Liq 219:232–238

    Article  CAS  Google Scholar 

  • Chinnammal Janaki E, Sailatha SG (2015) Synthesis, characteristics and antimicrobial activity of ZnO nanoparticles. Spectrochim Acta A Mol Biomol Spectrosc 144:17–22

    Article  PubMed  CAS  Google Scholar 

  • Daniel M-C, Astruc D (2004) Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology. Chem Rev 104(1):293–346

    Article  CAS  PubMed  Google Scholar 

  • Dhandapani P, Siddarth AS, Kamalasekaran S, Maruthamuthu S, Rajagopal G (2014) Bio-approach: Ureolytic bacteria mediated synthesis of ZnO nanocrystals on cotton fabric and evaluation of their antibacterial properties. Carbohydr Polym 103:448–455

    Article  CAS  PubMed  Google Scholar 

  • Dhanemozhi AC, Rajeswari V, Sathyajothi S (2017) Green synthesis of zinc oxide nanoparticle using green tea leaf extract for Supercapacitor application. Mater Today: Proc 4:660–667

    Google Scholar 

  • Do Kim K, Choi DW, Choa Y-H, Kim HT (2007) Optimization of parameters for the synthesis of zinc oxide nanoparticles by Taguchi robust design method. Colloids Surf A: Physicochem Eng Asp 311:170–173

    Article  CAS  Google Scholar 

  • Dobrucka R, Dugaszewska J (2016) Biosynthesis and antibacterial activity of ZnO nanoparticles using Trifolium pratense flower extract. Saudi J Biol Sci 23:517–523

    Article  CAS  PubMed  Google Scholar 

  • Dumbrava A, Berger D, Matei C, Radu MD, Gheorghe E (2018) Characterization and applications of a new composite material obtained by green synthesis, through deposition of zinc oxide onto calcium carbonate precipitated in green seaweeds extract. Ceram Int 44:4931–4936

    Article  CAS  Google Scholar 

  • El-Naggar ME, Shaarawy S, Hebeish AA (2018) Multifunctional properties of cotton fabrics coated with in situ synthesis of zinc oxide nanoparticles capped with date seed extract. Carbohydr Polym 181:307–316

    Article  CAS  PubMed  Google Scholar 

  • Elumalai K, Velmurugan S (2015) Green synthesis, characterization and antimicrobial activities of zinc oxide nanoparticles from the leaf extract of Azadirachta indica, (L.). Appl Surf Sci 345:329–333

    Article  CAS  Google Scholar 

  • Elumalai K, Velmurugan S, Ravi S, Kathiravan V, Ashokkumar S (2015a) Green synthesis of zinc oxide nanoparticles using Moringa Oleifera leaf extract and evaluation of its antimicrobial activity. Spectrochim Acta A 143:158e164

    Article  CAS  Google Scholar 

  • Elumalai K, Velmurugan S, Ravi S, Kathiravan V, Adaikala Raj G (2015b) Plant mediated synthesis of ZnO nanoparticles and their catalytic reduction of methylene blue and antimicrobial activity. Adv Powder Technol 26:1639–1651

    Article  CAS  Google Scholar 

  • Gandhi PR, Jayaseelan C, Mary RR, Mathivanan D, Suseem SR (2017) Acaricidal, pediculicidal and larvicidal activity of synthesized ZnO nanoparticles using Momordica charantia leaf extract against blood feeding parasites. Exp Parasitol 181:47e56

    Article  CAS  Google Scholar 

  • Gunalan S, Sivaraj R, Rajendran V (2012a) Green synthesized ZnO nanoparticles against bacterial and fungal pathogens. Prog Nat Sci: Mater Int 22(6):693–700

    Article  Google Scholar 

  • Gunalan S, Sivaraj R, Rajendran V (2012b) Green synthesized ZnO nanoparticles against bacterial and fungal pathogens. Mater Int 22(6):693–700

    Google Scholar 

  • Hamminga GM, Mul G, Moulijin JA (2004) Effects of impregnation with styrene and nano-zinc oxide on fire-retarding, physical, and mechanical properties of poplar wood. Chem Eng Sci 59:5479

    Article  CAS  Google Scholar 

  • Hussein MZ, Azmin WHWN, Mustafa M, Yahaya AH (2009) Bacillus cereus as a biotemplating agent for the synthesis of zinc oxide with raspberry- and plate-like structures. J Inorg Biochem 103:1145–1150

    Article  CAS  PubMed  Google Scholar 

  • Iravani S (2011) Green synthesis of metal nanoparticles using plants. Green Chem 13:2638e2650

    Article  CAS  Google Scholar 

  • Ishwarya R, Vaseeharan B, Kalyani S, Banumathi B, Govindarajan M, Alharbid NS, Kadaikunnan S, Al-anbrd MN, Khaled JM, Benelli G (2018) Facile green synthesis of zinc oxide nanoparticles using Ulva lactuca seaweed extract and evaluation of their photocatalytic, antibiofilm and insecticidal activity. J Photochem Photobiol B Biol 178:249–258

    Article  CAS  Google Scholar 

  • Ismail B, Nampoothiri KM (2010) Production, purification and structural characterization of an exopolysaccharide produced by a probiotic Lactobacillus plantarum MTCC 9510. Arch Microbiol 192:1049–1057

    Article  CAS  PubMed  Google Scholar 

  • Jamdagni P, Khatri P, Rana JS (2016) Green synthesis of zinc oxide nanoparticles using flower extract of Nyctanthes arbor-tristis and their antifungal activity. J King Saud Univ Sci 30(2):168–175

    Article  Google Scholar 

  • Joerger R, Klaus T, Granqvist CG (2000) Biologically produced silver carbon composite materials for optically functional thin film coatings. Adv Mater 12(6):407–409

    Article  CAS  Google Scholar 

  • Kandale A, Meena AK, Rao MM, Panda P, Mangal AK, Reddy G et al (2011) Marine algae: anintroduction, foodvalue andmedicinaluses. J Pharm Res 4(1):219e221

    Google Scholar 

  • Karthik S, Siva P, Balu KS, Suriyaprabha R, Rajendran V, Maaza M (2017) Acalypha indica–mediated green synthesis of ZnO nanostructures under differential thermal treatment: effect on textile coating, hydrophobicity, UV resistance, and antibacterial activity. Adv Powder Technol 28:3184–3194

    Article  CAS  Google Scholar 

  • Kato H (2011) In vitro assays: tracking nanoparticles inside cells. Nat Nanotechnol 6(3):139–140

    Article  CAS  PubMed  Google Scholar 

  • Kaviya S, Kabila S, Jayasree KV (2017) Hexagonal bottom-neck ZnO nano pencils: a study of structural, optical and antibacterial activity. Mater Lett 204:57–60

    Article  CAS  Google Scholar 

  • Kayaci F, Vempati S, Donmez I, Biyikli N, Uyar T (2014) Nanoscale 6:10224–10234

    Article  CAS  PubMed  Google Scholar 

  • Kim KD, Kim HT (2002) Preparation of silica nanoparticles determination of the optimal synthesis conditions for small and uniform particles. Colloids and surfaces a physicochemical and engineering aspects. J Sol Gel Sci Technol 25:183

    Article  CAS  Google Scholar 

  • Kim KD, Lee TJ, Kim HT (2003) Dynamics of population code for working memory in the prefrontal cortex. Colloids Surf A Physicochem Eng Asp 224:1

    Article  CAS  Google Scholar 

  • Kim KD, Han DN, Lee JB, Kim HT (2006) New and future developments in catalysis: solar photocatalysis. Scripta Mater 54:143

    Article  CAS  Google Scholar 

  • Kundu D, Hazra C, Chatterjee A, Chaudhari A, Mishra S (2014) Extracellular biosynthesis of zinc oxide nanoparticles using Rhodococcus pyridinivorans NT2: multifunctional textile finishing, biosafety evaluation and in vitro drug delivery in colon carcinoma. J Photochem Photobiol B Biol 140:194–204

    Article  CAS  Google Scholar 

  • Li WJ, Shi EW, Zheng YQ, Yin ZW (2001) Hydrothermal preparation of nanometer ZnO powders. J Mater Sci Lett 20:1381

    Article  CAS  Google Scholar 

  • Li X, Xu H, Chen Z-S, Chen G (2011) Biosynthesis of nanoparticles by microorganisms and their applications. J Nanomater 2011, Article ID 270974, 16 pages

    Google Scholar 

  • Lin HM, Tzeng SJ, Hsiau PJ, Tsai WL (1998) Low temperature electronics and low temperature cofired ceramic. Nanostruct Mater 10:465

    Article  CAS  Google Scholar 

  • Luechinger NA, Grass RN, Athanassiou EK, Stark WJ (2010) Bottom-up fabrication of metal/metal nano composites from nanoparticles of immiscible metals. Chem Mater 22(1):155–160

    Article  CAS  Google Scholar 

  • Madhumitha G, Elango G, Roopan SM (2016) Biotechnological aspects of ZnOnanoparticles: overview on synthesis and its applications. Appl Microbiol Biotechnol 100:571–581

    Article  CAS  PubMed  Google Scholar 

  • Mahendra C, Murali M, Manasa G, Ponnamma P, Abhilash MR, Lakshmeesha TR, Satish A, Amruthesh KN, Sudarshana MS (2017) Antibacterial and antimitotic potential of bio-fabricated zinc oxide nanoparticles of Cochlospermum religiosum (L.). Microb Pathog 110:620e629

    Article  CAS  Google Scholar 

  • Manilal A, Thajuddin N, Selvin J, Idhayadhulla A, Kumar RS, Sujith S (2011) In vitro mosquito larvicidal activity of marine algae against the human vectors, Culex quinquefasciatus (Say) and Aedes aegypti (Linnaeus) (Diptera: Culicidae). Int J Zool Res 7(3):272e278

    Article  Google Scholar 

  • Manna J, Goswami S, Shilpa N, Sahu N, Rana RK (2015) Biomimetic method to assemble nanostructured ag@ZnO on cotton fabrics: application as self-cleaning flexible materials with visible-light Photocatalysis and antibacterial activities. ACS Appl Mater Interfaces 7:8076–8082

    Article  CAS  PubMed  Google Scholar 

  • Matinisea N, Fukua XG, Kaviyarasua K, Mayedwa N, Maaza M (2017) ZnO nanoparticles via Moringa oleifera green synthesis: physical properties & mechanism of formation. Appl Surf Sci 406:339–347

    Article  CAS  Google Scholar 

  • Mohanpuria P, Rana NK, Yadav SK (2008) Biosynthesis of nanoparticles: technological concepts and future applications. J Nanopart Res 10(3):507–517

    Article  CAS  Google Scholar 

  • Molinski TF, Dalisay DS, Lievens SL, Saludes JP (2009) Drug development from marine natural products. Nat Rev Drug Discov 8(1):69e85

    Article  CAS  Google Scholar 

  • Murugan K, Roni M, Panneerselvam C, Aziz AT, Suresh U, Rajaganesh R, Aruliah R, Mahyoub JA, Trivedi S, Rehman H, Al-Aoh HAN, Kumar S, Higuchi A, Vaseeharan B, Wei H, Senthil-Nathan S, Canale A, Benelli G (2017) Sargassum wightii-synthesized ZnO nanoparticles reduce the fitness and reproduction of the malaria vector Anopheles stephensi and cotton bollworm Helicoverpa armigera. Phys Mol Plant Pathol 101(2018):202–213

    Article  CAS  Google Scholar 

  • Nagarajan S, Arumugam Kuppusamy K (2013) Extracellular synthesis of zinc oxide nanoparticle using seaweeds of gulf of Mannar, India. J Nanobiotechnol 11:39

    Article  CAS  Google Scholar 

  • Narayanan KB, Sakthivel N (2011) Green synthesis of biogenic metal nanoparticles by terrestrial and aquatic phototrophic and heterotrophic eukaryotes and biocompatible agents. Adv Colloid Interf Sci 169(2):59–79

    Article  CAS  Google Scholar 

  • Nava OJ, Luque PA, Gomez-Gutierrez CM, Vilchis-Nestor AR, Castro-Beltran A, Mota-Gonzalez ML, Olivas A (2017) Influence of Camellia sinensis extract on zinc oxide nanoparticle green synthesis. J Mol Struct 1134:121e125

    Article  CAS  Google Scholar 

  • Nethravathi PC, Shruthi GS, Suresh D, Udayabhanu, Nagabhushana H, Sharma SC (2015) Garcinia xanthochymus mediated green synthesis of ZnO nanoparticles: photoluminescence, photocatalytic and antioxidant activity studies. Ceram Int 41:8680–8687

    Article  CAS  Google Scholar 

  • O’Regan B, Schwartz DT (2000) Electrodeposited nanocomposite n–p heterojunctions for solid-state dye-sensitized photovoltaics. Adv Mater 12:1263

    Article  Google Scholar 

  • Pandimurugan R, Thambidurai S (2016) Novel seaweed capped ZnO nanoparticles for effective dye photodegradation and antibacterial activity. Adv Powder Technol 27:1062–1072

    Article  CAS  Google Scholar 

  • Pandimurugan R, Thambidurai S (2017) UV protection and antibacterial properties of seaweed capped ZnO nanoparticles coated cotton fabrics. Int J Biol Macromol 105:788–795

    Article  CAS  PubMed  Google Scholar 

  • Parashar UK, Saxena PS, Srivastava A (2009a) Bioinspired synthesis of silver nanoparticles. Dig J Nanomater Biostruct 4(1):159–166

    Google Scholar 

  • Parashar V, Parashar R, Sharma B, Pandey AC (2009b) Partenium leaf extract mediated synthesis of silver nanoparticles: a novel approach towards weed utilization. Dig J Nanomater Biostruct 4(1):45–50

    Google Scholar 

  • Patra JK, Baek K-H (2014) Green nanobiotechnology: factors affecting synthesis and characterization techniques. J Nanomater 2014, Article ID 417305, 12 pages

    Google Scholar 

  • Pavan Kumar MA, Suresh D, Nagabhushana H, Sharma SC (2015) Beta vulgaris aided green synthesis. of ZnO nanoparticles and their luminescence, photo-. catalytic and antioxidant properties. Eur Phys J Plus 130:109–116

    Article  CAS  Google Scholar 

  • Pavithra NS, Lingaraju K, Raghu GK, Nagaraju G (2017) Citrus maxima (Pomelo) juice mediated eco-friendly synthesis of ZnO nanoparticles: Applicationsto photocatalytic, electrochemical sensor and antibacterial activities. Mol Biomol Spectrosc 185:11–19

    Article  CAS  Google Scholar 

  • Raja Naika H, Lingaraju K, Manjunath K, Kumar D, Nagaraju G, Suresh D, Nagabhushana H (2015) Green synthesis of CuO nanoparticles using Gloriosa. superba L. extract and their antibacterial activity. J Taibah Univ Sci 9:7–12

    Article  Google Scholar 

  • Rajabia HR, Naghiha R, Kheirizadeh M, Sadatfaraji H, Mirzaei A, Alvand ZM (2017) Microwave assisted extraction as an efficient approach for biosynthesis of zinc oxide nanoparticles: synthesis, characterization, and biological properties. Mater Sci Eng C 78:1109–1118

    Article  CAS  Google Scholar 

  • Rajiv P, Rajeshwari S, Venckatesh R (2013) Spectrochimica Acta Part A: bio-fabrication of zinc oxide nanoparticles using leaf extract of Parthenium hysterophorus L. and its size-dependent antifungal activity against plant fungal pathogens. Mol Biomol Spectrosc 112:384–387

    Article  CAS  Google Scholar 

  • Raliya R, Tarafdar JC (2013) ZnO nanoparticle biosynthesis and its effect on phosphorous-mobilizing enzyme secretion and gum contents in clusterbean (Cyamopsis tetragonoloba L.). Agric Res 2(1):48–57

    Article  CAS  Google Scholar 

  • Ramesha M, Anbuvannan M, Viruthagiri G (2015) Green synthesis of ZnO nanoparticles using Solanum nigrum leaf extract and their antibacterial activity. Mol Biomol Spectrosc 136 (864–870

    Article  CAS  Google Scholar 

  • Rico CM, Majumdar S, Duarte-Gardea M, Peralta-Videa JR, Gardea-Torresdey JL (2011) Interaction of nanoparticles with edible plants and their possible implications in the food chain. J Agric Food Chem 59(8):3485–3498

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rosi NL, Mirkin CA (2005) Nanostructures in biodiagnostics. Chem Rev 105:1547–1562

    Article  CAS  PubMed  Google Scholar 

  • Sabir S, Arshad M, Chaudhari SK (2014) Zinc oxide nanoparticles for revolutionizing agriculture: synthesis and applications. Sci World J 925494:8

    Google Scholar 

  • Salem W, Leitner DR, Zingl FG, Schratter G, Prassl R, Goessler W, Reidl J, Schild S (2015) Antibacterial activity of silver and zinc nanoparticles against Vibrio cholera and enterotoxic Escherichia coli. Int J Med Microbiol 305:85–95

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Santhoshkumar J, Kumar SV, Rajeshkumar S (2017) Synthesis of zinc oxide nanoparticles using plant leaf extract against urinary tract infection pathogen. Res Effic Technol 3:459–465

    Google Scholar 

  • Saravanan M, Gopinath V, Chaurasia MK, Syed A, Ameen F, Purushothaman N (2018) Green synthesis of anisotropic zinc oxide nanoparticles with antibacterial and cytofriendly properties. Microb Pathog 115:57–63

    Article  CAS  PubMed  Google Scholar 

  • Shamaila S, Sajjad AKL, Ryma N-u-A, Farooqi SA, Jabeen N, Majeed S, Farooq I (2016) Review advancements in nanoparticle fabrication by hazard free eco-friendly green routes. Appl Mater Today 5:150–199

    Article  Google Scholar 

  • Shamsuzzaman AM, Khanam H, Aljawfi RN (2017) Biological synthesis of ZnO nanoparticles using C. albicans and studying their catalytic performance in the synthesis of steroidal pyrazolines. Arab J Chem 10:S1530–S1536

    Article  CAS  Google Scholar 

  • Siripireddy B, Mandal BK (2017) Facile green synthesis of zinc oxide nanoparticles by Eucalyptus globulus and their photocatalytic and antioxidant activity. Adv Powder Technol 28:785–797

    Article  CAS  Google Scholar 

  • Sonia S, Linda Jeeva Kumari H, Ruckmani K, Sivakumar M (2017) Antimicrobial and antioxidant potentials of biosynthesized colloidal zinc oxide nanoparticles for a fortified cold cream formulation: a potent nanocosmeceutical application. Mater Sci Eng C 79:581–589

    Article  CAS  Google Scholar 

  • Suganya P, Vaseeharan B, Vijayakumar S, Balan B, Govindarajan M, Alharbi NS, Kadaikunnan S, Khaled JM, Benelli G (2017) Biopolymer zein-coated gold nanoparticles: synthesis, antibacterial potential, toxicity and histopathological effects against the Zika virus vector Aedes aegypti. J Photochem Photobiol B 173:404–411

    Article  CAS  PubMed  Google Scholar 

  • Sundrarajan M, Ambika S, Bharathi K (2015) Plant-extract mediated synthesis of ZnO nanoparticles using Pongamia pinnata and their activity against pathogenic bacteria. Adv Powder Technol 26:1294–1299

    Article  CAS  Google Scholar 

  • Suresh D, Nethravathi PC, Udayabhanu MAPK, Raja Naika H, Nagabhushana H, Sharma SC (2015a) Chironji mediated facile green synthesis of ZnO nanoparticles and their photoluminescence, photodegradative, antimicrobial and antioxidant activities. Mater Sci Semicond Process 40:759–765760

    Article  CAS  Google Scholar 

  • Suresh D, Udayabhanu PCN, Lingaraju K, Rajanaika H, Sharma SC, Nagabhushana H (2015b) EGCG assisted green synthesis of ZnO nanopowders: Photodegradative, antimicrobial and antioxidant activities. Spectrochim Acta A 136:1467–1474

    Article  CAS  Google Scholar 

  • Suresh D, Shobharani RM, Nethravathi PC, Pavan Kumar MA, Nagabhushana H, Sharma SC (2015c) Artocarpus gomezianus aided green synthesis of ZnO nanoparticles: luminescence, photocatalytic and antioxidant properties. Spectrochim Acta A 141:128–134

    Article  CAS  Google Scholar 

  • Suresh D, Nethravathi PC, Udayabhanu, Rajanaika H, Nagabhushana H, Sharma SC (2015d) Green synthesis of multifunctional zinc oxide (ZnO) nanoparticles using Cassia fistula plant extract and their photodegradative, antioxidant and antibacterial activities. Mater Sci Semicond Process 31:446–454

    Article  CAS  Google Scholar 

  • Thakkar KN, Mhatre SS, Parikh RY (2010) Biological synthesis of metallic nanoparticles. Nanomedicine 6:257e262

    Google Scholar 

  • Thaya R, Malaikozhundan B, Vijayakumar S, Sivakamavalli J, Jeyasekar R, Shanthi S, Vaseeharan B, Ramasamy P, Sonawane A (2016) Chitosan coated Ag/ZnO nanocomposite and their antibiofilm, antifungal and cytotoxic effects on murine macrophages. Microb Pathog 100:124–132

    Article  CAS  PubMed  Google Scholar 

  • Tiwari DK, Behari J, Sen P (2008) Time and dose-dependent antimicrobial potential of Ag nanoparticles synthesized by top down approach. Curr Sci 95(5):647–655

    CAS  Google Scholar 

  • Turton R, Berry DA, Gardner TH, Miltz A (2004) Polymer nanocomposite for electro-optics: perspectives on processing technologies. Indian Eng Chem Res 43:1235

    Article  CAS  Google Scholar 

  • Udayabhanu PC, Nethravathi MA, Pavan Kumar D, Suresh K, Lingaraju H, Rajanaika H, Nagabhushana SCS (2015) Green synthesis of copper oxide (CuO) nanoparticles using banana peel extract and their photocatalytic activities. Mater Sci Semicond Process 33:81–88

    Article  CAS  Google Scholar 

  • Venkatachalam P, Priyank N, Manikandan K, Ganeshbabu I, Indiraarulselvi P, Geeth N, Muralikrishna K, Bhattacharya RC, Tiwari M, Sharma N, Sahi SV (2017) Enhanced plant growth promoting role of phycomolecules coated zinc oxide nanoparticles with P supplementation in cotton (Gossypium hirsutum L.). Plant Physiol Biochem 110:118e127

    Google Scholar 

  • Vijayakumar S, Vaseeharan B, Malaikozhundan B, Shobiya M (2016a) Laurus nobilis leaf extract mediated green synthesis of ZnO nanoparticles: characterization and biomedical applications. Biomed Pharmacother 84:1213–1222

    Article  CAS  PubMed  Google Scholar 

  • Vijayakumar S, Malaikozhundan B, Gobi N, Vaseeharan B, Murthy C (2016b) Protective effects of chitosan against the hazardous effects of zinc oxide nanoparticle in freshwater crustaceans Ceriodaphnia cornuta and Moina micrura. Limnologica 61:44–51

    Article  CAS  Google Scholar 

  • Vijayakumar S, Malaikozhundan B, Ramasamy P, Vaseeharan B (2016c) Assessment of biopolymer stabilized silver nanoparticle for their ecotoxicity on Ceriodaphnia cornuta and antibiofilm activity. J Environ Chem Eng 4:2076–2083

    Article  CAS  Google Scholar 

  • Vijayakumara S, Krishnakumar C, Arulmozhi P, Mahadevan S, Parameswari N (2018) Biosynthesis, characterization and antimicrobial activities of zinc oxide nanoparticles from leaf extract of Glycosmis pentaphylla (Retz.) DC. Microb Pathog 116:44–48

    Article  CAS  Google Scholar 

  • Vijayaraghavan K, Ashokkumar T (2017) Plant-mediated biosynthesis of metallic nanoparticles: a review of literature, factors affecting synthesis, characterization techniques and applications. J Environ Chem Eng 5:4866–4883

    Article  CAS  Google Scholar 

  • Wang ZS, Huang CH, Huang YY, Hou YJ, Xie PH, Zhang BW, Cheng HM (2001) Synthesis and physicochemical characterization of ZnOPorphyrin based hybrid materials for potential photovoltaic applications. Chem Mater 13:678

    Article  CAS  Google Scholar 

  • Wang X, Ding Y, Summers CJ, Wang ZL (2004) Large scale synthesis of six-nanometer-wide ZnO nanobelts. J Phys Chem B 108(26):8773–8777

    Article  CAS  Google Scholar 

  • Yan X, Shumin W, Lib X, Meng H, Zhanga X, Wang Z, Han Y (2017) Ag nanoparticle-functionalized ZnO micro-flowers for enhanced photodegradation of herbicide derivatives. Chem Phys Lett 679:119–126

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Rajeshkumar, S., Sandhiya, D. (2020). Biomedical Applications of Zinc Oxide Nanoparticles Synthesized Using Eco-friendly Method. In: Shukla, A. (eds) Nanoparticles and their Biomedical Applications. Springer, Singapore. https://doi.org/10.1007/978-981-15-0391-7_3

Download citation

  • DOI: https://doi.org/10.1007/978-981-15-0391-7_3

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-15-0390-0

  • Online ISBN: 978-981-15-0391-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics