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Fungus-Mediated Nanoparticles: Characterization and Biomedical Advances

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Nanoparticles in Medicine

Abstract

Development of nature-friendly approaches for synthesis of nanoparticles by favorable microorganisms—for example, using fungal cultures—has played an important role in nanotechnology. Two types of synthesis have been established: intracellular synthesis and extracellular synthesis. Intracellular synthesis involves carriage of ions into microbial cells to form nanoparticles in the presence of enzymes. Extracellular synthesis of nanoparticles involves trapping of ions on the surface of cells and reducing the ions in the presence of enzymes. These methods have been applied to agriculture, drug delivery systems, biomedicines, etc. They are able to produce nanoparticles for nanostructure combinations with organic or inorganic chemicals. The fungal mediated nanoparticles are characterized using some analytical techniques are demonstrated. Their size and shape can be estimated by X-ray powder diffraction analysis, atomic force microscopy, thermogravimetric analysis, Fourier-transform infrared spectroscopy, scanning electron microscopy, and transmission electron microscopy.

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References

  • Ahmad A, et al. Enzyme mediated extracellular synthesis of CdS nanoparticles by the fungus, Fusarium oxysporum. J Am Chem Soc. 2002;124(41):12108–9.

    CAS  PubMed  Google Scholar 

  • Andries M, et al. The effect of visible light on gold nanoparticles and some bioeffects on environmental fungi. Int J Pharm. 2016;505(1–2):255–61. https://doi.org/10.1016/j.ijpharm.2016.04.004.

    Article  CAS  PubMed  Google Scholar 

  • Balaji DS, et al. Extracellular biosynthesis of functionalized silver nanoparticles by strains of Cladosporium cladosporioides fungus. Colloids Surf B: Biointerfaces. 2009;68(1):88–92.

    CAS  PubMed  Google Scholar 

  • Barabadi H, et al. Microbial mediated preparation, characterization and optimization of gold nanoparticles. Braz J Microbiol. 2014;45(4):1493–501.

    CAS  PubMed  Google Scholar 

  • Basavaraja S, et al. Extracellular biosynthesis of silver nanoparticles using the fungus Fusarium semitectum. Mater Res Bull. 2008;43(5):1164–70.

    CAS  Google Scholar 

  • Castro ME, Cottet L, Castillo A. Biosynthesis of gold nanoparticles by extracellular molecules produced by the phytopathogenic fungus Botrytis cinerea. Mater Lett. 2014;115:42–4. https://doi.org/10.1016/j.matlet.2013.10.020.

    Article  CAS  Google Scholar 

  • Chauhan A, et al. Fungus-mediated biological synthesis of gold nanoparticles: potential in detection of liver cancer. Int J Nanomedicine. 2011;6:2305–19.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Chauhan R, Reddy A, Abraham J. Biosynthesis and antimicrobial potential of silver and zinc oxide nanoparticles using Candida diversa strain JA1. Der Pharma Chemica. 2014;6(3):39–47.

    Google Scholar 

  • Chauhan R, Reddy A, Abraham J. Biosynthesis of silver and zinc oxide nanoparticles using Pichia fermentans JA2 and their antimicrobial property. Appl Nanosci. 2015;5(1):63–71. https://doi.org/10.1007/s13204-014-0292-7.

    Article  CAS  Google Scholar 

  • Cuevas R, et al. Extracellular biosynthesis of copper and copper oxide nanoparticles by Stereum hirsutum, a native white-rot fungus from Chilean forests. J Nanomater. 2015;2015:1–7.

    Google Scholar 

  • Elahian F, Reiisi S, Shahidi A, Mirzaei SA. High-throughput bioaccumulation, biotransformation, and production of silver and selenium nanoparticles using genetically engineered Pichia pastoris. Nanomedicine. 2017;13(3):853–61. https://doi.org/10.1016/j.nano.2016.10.009.

    Article  CAS  PubMed  Google Scholar 

  • Elgorban AM, et al. Extracellular synthesis of silver nanoparticles using Aspergillus versicolor and evaluation of their activity on plant pathogenic fungi. Mycosphere. 2016;7(6):844–52.

    Google Scholar 

  • El-Sonbaty SM. Fungus-mediated synthesis of silver nanoparticles and evaluation of antitumor activity. Cancer Nanotechnol. 2013;4(4–5):73–9.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Fatima F, et al. Antimicrobial and immunomodulatory efficacy of extracellularly synthesized silver and gold nanoparticles by a novel phosphate solubilizing fungus Bipolaris tetramera. BMC Microbiol. 2015;15(1):1–10.

    Google Scholar 

  • Gajbhiye M, et al. Fungus-mediated synthesis of silver nanoparticles and their activity against pathogenic fungi in combination with fluconazole. Nanomedicine. 2009;5(4):382–6. https://doi.org/10.1016/j.nano.2009.06.005.

    Article  CAS  PubMed  Google Scholar 

  • Ingle A, Rai M, Gade A, Bawaskar M. Fusarium solani: a novel biological agent for the extracellular synthesis of silver nanoparticles. J Nanopart Res. 2009;11(8):2079–85.

    CAS  Google Scholar 

  • Jaidev LR, Narasimha G. Fungal mediated biosynthesis of silver nanoparticles, characterization and antimicrobial activity. Colloids Surf B: Biointerfaces. 2010;81(2):430–3. https://doi.org/10.1016/j.colsurfb.2010.07.033.

    Article  CAS  PubMed  Google Scholar 

  • Joshi CG, et al. Biogenic synthesis of gold nanoparticles by marine endophytic fungus-Cladosporium cladosporioides isolated from seaweed and evaluation of their antioxidant and antimicrobial properties. Process Biochem. 2017;63(March):137–44. https://doi.org/10.1016/j.procbio.2017.09.008.

    Article  CAS  Google Scholar 

  • Kathiresan K, Manivannan S, Nabeel MA, Dhivya B. Studies on silver nanoparticles synthesized by a marine fungus, Penicillium fellutanum isolated from coastal mangrove sediment. Colloids Surf B: Biointerfaces. 2009;71(1):133–7.

    CAS  PubMed  Google Scholar 

  • Krishnan S, Narayan S, Chadha A. Whole resting cells vs. cell free extracts of Candida parapsilosis ATCC 7330 for the synthesis of gold nanoparticles. AMB Express. 2016;6(1):92.

    PubMed  PubMed Central  Google Scholar 

  • Sandana Mala JG, Rose C. Facile production of ZnS quantum dot nanoparticles by Saccharomyces cerevisiae MTCC 2918. J Biotechnol. 2014;170(1):73–8. https://doi.org/10.1016/j.jbiotec.2013.11.017.

    Article  CAS  PubMed  Google Scholar 

  • Patel BH, Channiwala MZ, Chaudhari SB, Mandot AA. Biosynthesis of copper nanoparticles; its characterization and efficacy against human pathogenic bacterium. J Environ Chem Eng. 2016;4(2):2163–9. https://doi.org/10.1016/j.jece.2016.03.046.

    Article  CAS  Google Scholar 

  • Qu Y, et al. Biosynthesis of gold nanoparticles by Aspergillum sp. WL-Au for degradation of aromatic pollutants. Physica E. 2017;88(January):133–41. https://doi.org/10.1016/j.physe.2017.01.010.

    Article  CAS  Google Scholar 

  • Quester K, Avalos-Borja M, Castro-Longoria E. Controllable biosynthesis of small silver nanoparticles using fungal extract. J Biomater Nanobiotechnol. 2016;7(2):118–25.

    CAS  Google Scholar 

  • Rajakumar G, et al. Fungus-mediated biosynthesis and characterization of TiO2 nanoparticles and their activity against pathogenic bacteria. Spectrochim Acta A Mol Biomol Spectrosc. 2012;91:23–9. https://doi.org/10.1016/j.saa.2012.01.011.

    Article  CAS  PubMed  Google Scholar 

  • Sanghi R, Verma P. A facile green extracellular biosynthesis of CdS nanoparticles by immobilized fungus. Chem Eng J. 2009a;155(3):886–91.

    CAS  Google Scholar 

  • Sanghi R, Verma P. Biomimetic synthesis and characterisation of protein capped silver nanoparticles. Bioresour Technol. 2009b;100(1):501–4.

    CAS  PubMed  Google Scholar 

  • Sastry M, Ahmad A, Islam Khan M, Kumar R. Biosynthesis of metal nanoparticles using fungi and actinomycete. Curr Sci. 2003;85(2):162–70.

    CAS  Google Scholar 

  • Sawle BD, et al. Biosynthesis and stabilization of Au and Au–Ag alloy nanoparticles by fungus, Fusarium semitectum. Sci Technol Adv Mater. 2008;9(3):035012.

    Google Scholar 

  • Shankar SS, Ahmad A, Pasricha R, Sastry M. Bioreduction of chloroaurate ions by geranium leaves and its endophytic fungus yields gold nanoparticles of different shapes. J Mater Chem. 2003;13(7):1822.

    CAS  Google Scholar 

  • Shantkriti S, Rani P. Original research article biological synthesis of copper nanoparticles using Pseudomonas fluorescens. Int J Curr Microbiol App Sci. 2014;3(9):374–83.

    Google Scholar 

  • Soni N, Prakash S. Efficacy of fungus mediated silver and gold nanoparticles against Aedes aegypti larvae. Parasitol Res. 2012;110(1):175–84.

    PubMed  Google Scholar 

  • Tripathi RM, et al. Ultra-sensitive detection of mercury(II) ions in water sample using gold nanoparticles synthesized by Trichoderma harzianum and their mechanistic approach. Sensors Actuators B Chem. 2014;204:637–46. https://doi.org/10.1016/j.snb.2014.08.015.

    Article  CAS  Google Scholar 

  • Velhal SG, Kulkarni SD, Latpate RV. Fungal mediated silver nanoparticle synthesis using robust experimental design and its application in cotton fabric. Int Nano Lett. 2016;6(4):257–64. https://doi.org/10.1007/s40089-016-0192-9.

    Article  CAS  Google Scholar 

  • Vigneshwaran N, et al. Biological synthesis of silver nanoparticles using the fungus Aspergillus flavus. Mater Lett. 2007;61(6):1413–8.

    CAS  Google Scholar 

  • Vigneshwaran N, et al. Biomimetics of silver nanoparticles by white rot fungus, Phanerochaete chrysosporium. Colloids Surf B Biointerfaces. 2006;53(1):55–9.

    CAS  PubMed  Google Scholar 

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Rajeshkumar, S., Sivapriya, D. (2020). Fungus-Mediated Nanoparticles: Characterization and Biomedical Advances. In: Shukla, A. (eds) Nanoparticles in Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-13-8954-2_7

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  • DOI: https://doi.org/10.1007/978-981-13-8954-2_7

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