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Magnetic Nanomedicine

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Nanomedicine in Brain Diseases

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Abstract

Nanotechnology emerged as a promising field of science with a diversity of applications in energy storage, biotechnology, medicine, sensing, and healthcare monitoring and in each aspect of nature. Owing to the significant characteristics of the smaller size, easy modification, and tunable physical and chemical properties, magnetic nanomaterials have gained potential fame in the nanomedicine field. In terms of treatment and diagnosis, magnetic nanoparticles (MNP) cannot be replaced with any other material. Surface functionalization and coating of ferromagnetic and superparamagnetic nanoparticles not only make them biocompatible but also effective for drug delivery and killing tumor cells. In this book chapter, we highlighted the emerging applications of magnetic nanoparticles, from synthesis to potential applications. Specifically, brief introduction of magnetic nanomaterials and their physical properties is discussed in detail. Further, the facile synthesis methods to prepare MNPs and recent developments in MNPs as magnetic hyperthermia agents, as a drug transporter, and use in magnetic resonance imaging as a contrast agents are also elaborated profoundly.

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Acknowledgments

The authors would like to thank the continuous support by National Key R&D Program of China (2018YFC0910601), Natural Science Foundation of China (U1432114 to Aiguo Wu and 81950410638 and 81650410654 to M. Zubair Iqbal), Zhejiang Province Financial Supporting (2017C03042, LY18H180011), and the Science & Technology Bureau of Ningbo City (2015B11002, 2017C110022). Furthermore, the authors also acknowledge Shanghai Synchrotron Radiation Facility at Line BL15U (No. h15 sr0021) used for X-ray fluorescence imaging and National Synchrotron Radiation Laboratory in Hefei used for soft X-ray imaging (No. 2016-HLS-PT-002193).

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Authors and Affiliations

  1. Department of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou, People’s Republic of China

    M. Zubair Iqbal

  2. Cixi Institute of Biomedical Engineering, CAS Key Laboratory of Magnetic Materials and Devices, & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province, & Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, People’s Republic of China

    M. Zubair Iqbal, Gohar Ijaz Dar & Aiguo Wu

  3. Division of Polymer and Composite Materials, Ningbo Institute of Material Technology and Engineering, Chinese Academy of Sciences, Ningbo, People’s Republic of China

    Israt Ali

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  1. M. Zubair Iqbal
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  2. Gohar Ijaz Dar
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  3. Israt Ali
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  4. Aiguo Wu
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Corresponding author

Correspondence to Aiguo Wu .

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Editors and Affiliations

  1. State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, Tianjin, China

    Xue Xue

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Iqbal, M.Z., Dar, G.I., Ali, I., Wu, A. (2019). Magnetic Nanomedicine. In: Xue, X. (eds) Nanomedicine in Brain Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-13-8731-9_10

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