Abstract
Cervical cancer is the second most common cancer in females in India. A Pap smear screening is most efficient and prominent to detect the abnormality in cells. Pap smear test is time-consuming and sometimes gives the wrong result by human experts. In India, a shortage of pathologist is there in rural areas. Automated systems using image processing and machine learning techniques help the pathologist to take correct decisions. In this paper, two data sets are generated from one pathologist center. The first data set contains 300 single cells and the second contains 50 multiple cell images for the validation of work. In a single cell, nucleus and cytoplasm both are extracted from the cell, but in multiple cells, only the nuclei are extracted due to overlapping of cells. Edges have been enhanced by sharpening function, and the multi-threshold values and morphological operations have been used for the segmentation of cell. Shape-based features have extracted from a multiple cell and single cell images. Support Vector Machine (SVM) and Artificial Neural Network (ANN) is applied to improve the performance of classification using 10 fold cross-validation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Cancer Cases in India Likely to Soar 25% By 2020: ICMR - Times of India. www.timesofindia.indiatimes.com/india/Cancer-cases-in-India-likely-to-soar-25-by-2020-ICMR/articleshow/52334632.cms. Accessed 16 June 2017
Sreedevi, A., Javed, R., Dinesh, A.: Epidemiology of cervical cancer with special focus on India. Int. J. Women’s Health 7, 405–14 (2015)
Tan, S.Y., Tatsumura, Y.: George Papanicolaou (1883–1962): discoverer of the pap smear. Singap. Med. J. 56(10), 586 (2015)
Plissiti, M.E., Nikou, C., Charachanti, A.: Watershed-based segmentation of cell nuclei boundaries in Pap smear images. In: Proceeding of the 10th IEEE International Conference on Information Technology and Application in Biomedicine, pp. 1–4 (2010)
Kenny, S.P.K., Victor, S.P.: A comparative analysis of single and combination feature extraction techniques for detecting cervical cancer lesions. ICTACT J. Image Video Process. 6(3), 1167–1173 (2016)
Peng, Y., et al.: Clustering nuclei using machine learning techniques. In: 2010 IEEE/ICME International Conference on Complex Medical Engineering (CME), pp. 52–57 (2010)
Cheng, F.-H., Hsu, N.-R.: Automated cell nuclei segmentation from microscopic images of cervical smear. In: International Conference on Applied System Innovation (ICASI), pp. 1–4 (2016)
Arya, M., Mittal, N., Singh, G.: Fuzzy-based classification for cervical dysplasia using smear images. In: Sa, P.K., Bakshi, S., Hatzilygeroudis, I.K., Sahoo, M.N. (eds.) Recent Findings in Intelligent Computing Techniques. AISC, vol. 708, pp. 441–449. Springer, Singapore (2018). https://doi.org/10.1007/978-981-10-8636-6_46
Kaaviya, S., Saranyadevi, V., Nirmala, M.: PAP smear image analysis for cervical cancer detection. In: 2015 IEEE International Conference on Engineering and Technology (ICETECH), pp. 1–4 (2015)
Mahanta, L.B., Nath, D.C., Nath, C.K.: Cervix cancer diagnosis from pap smear Images using structure based segmentation and shape analysis. J. Emerg. Trends Comput. Inf. Sci. 3(2), 245–249 (2012)
Lakshmi, G.K., Krishnaveni, K.: Multiple feature extraction from cervical cytology images by Gaussian mixture model. In: World Congress on Computing and communication Technologies (WCCCT), pp. 309–311 (2014)
Athinarayanan, S., Srinath, M.V.: Classification of cervical cancer cells in PAP smear the screening test. ICTACT J. Image Video Process. 6(4), 1234–1238 (2016)
Sukumar, P., Gnanamurthy, R.K.: Computer aided detection of cervical cancer using pap smear images based on hybrid classifier. Int. J. Appl. Eng. Res. 10(8), 21021–21032 (2015). Research India Publications
Arya, M., Mittal, N., Singh, G.: Texture-based feature extraction of smear images for the detection of cervical cancer. IET Comput. Vis. 12(8), 1049–1059 (2018)
Kale, A., Aksoy, S.: Segmentation of cervical cell images. In: 20th International Conference on Pattern Recognition (ICPR) Istanbul, pp. 2399–2402 (2010)
Poonam, S.N., Vivek, M., Sharan, P.: Automated cervical cancer detection using photonic crystal based bio-sensor. In: IEEE International Advance Computing Conference (IACC), pp. 1174–1178 (2015)
Sharma, M., Singh, S.K., Agrawal, P., Madaan, V.: Classification of clinical dataset of cervical cancer using KNN. Indian J. Sci. Technol. 9(28), 1–5 (2016)
Sajeena, T.A., Jereesh, A.S.: Automated cervical cancer detection through RGVF segmentation and SVM classification. In: 2015 International Conference on Computing and Network Communications (CoCoNet), pp. 663–669 (2015)
Martin, L., Exbrayat, M.: Pap-smear classification (2003)
Acknowledgements
We should like to thank Dr. Archana Pareek and Dr. Mukesh Rathore for providing us Pap smear slides from her pathology lab and for helping us to capture images with the help of microscope.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Arya, M., Mittal, N., Singh, G. (2019). Cervical Cancer Detection Using Single Cell and Multiple Cell Histopathology Images. In: Somani, A., Ramakrishna, S., Chaudhary, A., Choudhary, C., Agarwal, B. (eds) Emerging Technologies in Computer Engineering: Microservices in Big Data Analytics. ICETCE 2019. Communications in Computer and Information Science, vol 985. Springer, Singapore. https://doi.org/10.1007/978-981-13-8300-7_17
Download citation
DOI: https://doi.org/10.1007/978-981-13-8300-7_17
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-13-8299-4
Online ISBN: 978-981-13-8300-7
eBook Packages: Computer ScienceComputer Science (R0)