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0-1 Integer Programming Based on DNA Tetrahedral Probe

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Computational Intelligence and Intelligent Systems (ISICA 2018)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 986))

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Abstract

It is difficult to find an effective algorithm for solving NP complete problems such as integer programming. The nanostructure constructed by DNA origami combines huge parallelism and massive storage capacity of DNA computing. In the calculation process, it can effectively avoid the number of experimental operations required by other DNA computing models. It greatly reduces the time consumption and the rate of misinterpretation, thus providing an effective way to efficiently solve integer programming. DNA tetrahedron is a nanostructure constructed by origami. It has stable structure, good toughness and compression resistance, simple production process, high yield, rich functional modification sites, good biocompatibility, but also resistance to a variety of specific or non-specific nuclease. Therefore it can reduce the misinterpretation rate of biochemical reactions using DNA tetrahedron and DNA single strand to construct probes, finding the true solution according to the constraint condition. And then it can improve the computational efficiency of the model.

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Acknowledgment

This project is supported by National Natural Science Foundation of China (No. 61702008, No. 61672001) and Anhui Natural Science Foundation (No. 1808085MF193).

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Authors and Affiliations

  1. School of Mathematics and Big Data, Anhui University of Science and Technology, Huainan, Anhui, China

    Jing Yang, Xinmu Yang, Zhixiang Yin, Zhang Qiang & Jianzhong Cui

  2. School of Computer, Dalian University of Technology, Dalian, Liaoning, China

    Zhang Qiang

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  1. Jing Yang
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  2. Xinmu Yang
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  3. Zhixiang Yin
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  4. Zhang Qiang
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  5. Jianzhong Cui
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Correspondence to Zhixiang Yin .

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Editors and Affiliations

  1. School of Information Science and Technology, Jiujiang University, Jiujiang, China

    Hu Peng

  2. School of Information Science and Technology, Jiujiang University, Jiujiang, China

    Changshou Deng

  3. School of Computer, Wuhan University, Wuhan, China

    Zhijian Wu

  4. School of Computer Science and Engineering, The University of Aizu, Aizu-Wakamatsu, Fukushima, Japan

    Yong Liu

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Yang, J., Yang, X., Yin, Z., Qiang, Z., Cui, J. (2019). 0-1 Integer Programming Based on DNA Tetrahedral Probe. In: Peng, H., Deng, C., Wu, Z., Liu, Y. (eds) Computational Intelligence and Intelligent Systems. ISICA 2018. Communications in Computer and Information Science, vol 986. Springer, Singapore. https://doi.org/10.1007/978-981-13-6473-0_9

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  • DOI: https://doi.org/10.1007/978-981-13-6473-0_9

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  • Online ISBN: 978-981-13-6473-0

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