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Critical Care Management of Guillain-Barré Syndrome

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Abstract

Guillain-Barré syndrome (GBS), also called acute inflammatory demyelinating polyradiculoneuropathy (AIDP), is an inflammatory disorder affecting the peripheral nervous system that is characterized by acute or subacute onset and typically monophasic course of the disease. Some patients with this disorder need hospitalization in an intensive care unit (ICU). Among neuromuscular disorders, only several ones require monitoring and treatment at ICUs, namely, GBS, amyotrophic lateral sclerosis, and acute myasthenia gravis. Management of these patients in ICU normally includes specific therapy, vital signs’ monitoring, treatment of systemic complications, as well as the elimination of autonomic nervous system disorders.

GBS is considered the most common cause of inflammatory polyneuropathies, the annual frequency of which is estimated as 1–3 cases per 100,000 people.

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Bril, E.V., Popugaev, K.A., Udalov, Y.D., Parinov, O.V., Zabelin, M.V., Samoilov, A.S. (2019). Critical Care Management of Guillain-Barré Syndrome. In: Prabhakar, H., Ali, Z. (eds) Textbook of Neuroanesthesia and Neurocritical Care. Springer, Singapore. https://doi.org/10.1007/978-981-13-3390-3_4

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