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The Visual Field Defects of Leber’s Disease

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Optic Disorders and Visual Field

Part of the book series: Advances in Visual Science and Eye Diseases ((AVSED,volume 2))

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Abstract

Leber’s hereditary optic neuropathy (LHON) is a maternal genetic disorder caused by point mutations of mitochondrial DNA (mtDNA). Visual field damage in LHON is mostly central defects of various sizes and shapes. In this section, several selected cases of the mutation of the same mtDNA are analyzed, and the pathogenesis of LHON is discussed at the molecular level.

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References

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Author information

Authors and Affiliations

  1. Shandong Eye Institute, Qingdao Eye Hospital, Qingdao, China

    Xiaojing Pan

  2. Shenzhen Eye Hospital, Shenzhen University, Shenzhen, China

    Ning Fan & Xuyang Liu

  3. Xiamen Eye Center of Xiamen University, Xiamen, China

    Xuyang Liu

Authors
  1. Xiaojing Pan
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  2. Ning Fan
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  3. Xuyang Liu
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Editor information

Editors and Affiliations

  1. Beijing Tongren Hospital, Capital Medical University, Beijing, China

    Ningli Wang

  2. Xiamen Eye Center of Xiamen University, Xiamen, China

    Xuyang Liu

  3. Shenzhen Eye Hospital, Shenzhen University, Shenzhen, China

    Ning Fan

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© 2019 Springer Nature Singapore Pte Ltd. & People's Medical Publishing House, PR of China

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Pan, X., Fan, N., Liu, X. (2019). The Visual Field Defects of Leber’s Disease. In: Wang, N., Liu, X., Fan, N. (eds) Optic Disorders and Visual Field. Advances in Visual Science and Eye Diseases, vol 2. Springer, Singapore. https://doi.org/10.1007/978-981-13-2502-1_34

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  • DOI: https://doi.org/10.1007/978-981-13-2502-1_34

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-13-2501-4

  • Online ISBN: 978-981-13-2502-1

  • eBook Packages: MedicineMedicine (R0)

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