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Characterization of Electrochemical Transducers for Biosensor Applications

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Multifaceted Protocol in Biotechnology

Abstract

Biosensors are devices that detect and report the presence or quantity of a particular analyte. Among the biosensor components, a physicochemical transducer measures physical and chemical changes from analyte-recognition interactions where products, by-products, intermediates, or physical changes are converted into a measurable signal. The character of the transducer determines the performance of a biosensor; hence the characterization of the transduction is crucial in the design of a biosensor. This chapter describes electrochemical characterization of the transducer layer of a biosensor via cyclic voltammetry.

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References

  • An YK, Kim MK, Sohn H (2014) Piezoelectric transducers for assessing and monitoring civil infrastructures. Sensor technologies for civil infrastructures: sensing hardware and data collection methods for performance assessment, pp 1, 86

    Chapter  Google Scholar 

  • Baghayeri M, Zare EN, Hasanzadeh R (2014) Facile synthesis of PSMA-g-3ABA/MWCNTs nanocomposite as a substrate for hemoglobin immobilization: application to catalysis of H2O2. Mater Sci Eng C 39:213–220

    Article  CAS  Google Scholar 

  • Bartlett PN (2008) Bioelectrochemistry: fundamentals, experimental techniques, and applications. Wiley, Chichester

    Book  Google Scholar 

  • Berrettoni C, Berneschi S, Bernini R, Giannetti A, Grimaldi IA, Persichetti G et al (2014) Optical monitoring of therapeutic drugs with a novel fluorescence-based POCT device. Proc Eng 87:392–395

    Article  CAS  Google Scholar 

  • Du J, Yue R, Ren F, Yao Z, Jiang F, Yang P, Du Y (2013) Simultaneous determination of uric acid and dopamine using a carbon fiber electrode modified by layer-by-layer assembly of graphene and gold nanoparticles. Gold Bull 46:137–144

    Article  Google Scholar 

  • Gao K, Shao Z, Wu X, Wang X, Li J, Zhang Y, Wang W, Wang F (2013) Cellulose nanofibers/reduced graphene oxide flexible transparent conductive paper. Carbohydr Polym 97:243–251

    Article  CAS  PubMed  Google Scholar 

  • Han YD, Park YM, Chun HJ, Yoon HC (2015) A low-cost optical transducer is utilizing common electronics components for the gold nanoparticle-based immunosensing application. Sensors Actuators B Chem 220:233–242

    Article  CAS  Google Scholar 

  • Huang X, Yin Z, Wu S, Qi X, He Q, Zhang Q, Yan Q, Boey F, Zhang H (2011) Graphene-based materials: synthesis, characterization, properties, and applications. Small 7(14):1876–1902

    Article  CAS  PubMed  Google Scholar 

  • Li X, Zhong A, Wei S, Luo X, Liang Y, Zhu Q (2015) Polyelectrolyte functionalized gold nanoparticles-reduced graphene oxide nanohybrid for electrochemical determination of aminophenol isomers. Electrochim Acta 164:203–210

    Article  CAS  Google Scholar 

  • Luong JH, Male KB, Glennon JD (2008) Biosensor technology: technology push versus market pull. Biotechnol Adv 26(5):492–500

    Article  CAS  PubMed  Google Scholar 

  • Nia PM, Meng WP, Lorestani F, Mahmoudian MR, Alias Y (2015) Electrodeposition of copper oxide/polypyrrole/reduced graphene oxide as a nonenzymatic glucose biosensor. Sensors Actuators B Chem 209:100–108

    Article  Google Scholar 

  • Palanisamy S, Vilian ATE, Chen S (2012) Direct electrochemistry of glucose oxidase at reduced graphene oxide/zinc oxide composite modified electrode for glucose sensor. Int J Electrochem Sci 7:2153–2163

    CAS  Google Scholar 

  • Park W, Hu J, Jauregui LA, Ruan X, Chen YP (2014) Electrical and thermal conductivities of reduced graphene oxide/polystyrene composites. Appl Phys Lett 104:113101

    Article  Google Scholar 

  • Perumal V, Hashim U (2014) Advances in biosensors: principle, architecture and applications. J Appl Biomed 12(1):1–15

    Article  Google Scholar 

  • Royal Society of Chemistry (2015). Composites. Retrieved from www.rsc.org/Education/Teachers/Resources/Inspirational/resources/4.3.1.pdf

  • Serhane R, Abdelli-Messaci S, Lafane S, Khales H, Aouimeur W, Hassein-Bey A, Boutkedjirt T (2014) Pulsed laser deposition of piezoelectric ZnO thin films for bulk acoustic wave devices. Appl Surf Sci 288:572–578

    Article  CAS  Google Scholar 

  • Shi A, Wang J, Han X, Fang X, Zhang Y (2014) A sensitive electrochemical DNA biosensors based on gold nanomaterial and graphene amplified signal. Sens Actuator B Chem 200:206–212

    Article  CAS  Google Scholar 

  • Singh V, Joung D, Zhai L, Das S, Khondaker SI, Seal S (2011) Graphene based materials: past, present and future. Prog Mater Sci 56:1178–1271

    Article  CAS  Google Scholar 

  • Tabrizi MA, Varkani JN (2014) Green synthesis of reduced graphene oxide decorated with gold nanoparticles and its glucose sensing application. Sens Actuator B Chem 202:475–482

    Article  Google Scholar 

  • Tian K, Prestgard M, Tiwari A (2014) A review of recent advances in nonenzymatic glucose sensors. Mater Sci Eng C 41:100–118

    Article  CAS  Google Scholar 

  • Turner AP, Karube I, Wilson GS (1990) Biosensors: fundamentals and applications. Oxford University Press, Oxford

    Google Scholar 

  • Vereshchagina E, Tiggelaar RM, Sanders RGP, Wolters RAM, Gardeniers JGE (2015) Low power micro-calorimetric sensors for analysis of gaseous samples. Sens Actuators B Chem 206:772–787

    Article  CAS  Google Scholar 

  • Wan X, Zhao J, Wang M (2010) A novel design of the sensor head for avoiding the influence of the reflection phase shift in optical current transducer. Opt Lasers Eng 48(3):325–328

    Article  Google Scholar 

  • Wang C, Ye F, Wu H, Qian Y (2013a) Depositing Au nanoparticles onto graphene sheets for simultaneous electrochemical detection ascorbic acid, dopamine and uric acid. Int J Electrochem Sci 8:2440–2448

    CAS  Google Scholar 

  • Wang MY, Shen T, Wang M, Zhang D, Chen J (2013b) One-pot green synthesis of Ag nanoparticles-decorated reduced graphene oxide for efficient nonenzymatic H2O2 biosensor. Mater Lett 107:311–314

    Article  CAS  Google Scholar 

  • Yakovenko VM (2012) Novel method for photovoltaic energy conversion using surface acoustic waves in piezoelectric semiconductors. Phys B Condens Matter 407(11):1969–1972

    Article  CAS  Google Scholar 

  • Yang J, Gunasekaran S (2012) Electrochemically reduced graphene oxide sheets for use in high performance supercapacitors. Carbon 51:36–44

    Article  Google Scholar 

  • Yang J, Deng S, Lei J, Ju H, Gunasekaran S (2011) Electrochemical synthesis of reduced graphene sheet-AuPd alloy nanoparticle composites for enzymatic biosensing. Biosens Bioelectron 29:159–166

    Article  CAS  PubMed  Google Scholar 

  • Zhang Y, Wang Y, Jia J, Wang J (2012) Nonenzymatic glucose sensor based on graphene oxide and electrospun NiO nanofibers. Sens Actuator B Chem 171–172:580–587

    Article  Google Scholar 

  • Zheng Q, Cheng J, Liu X, Bai H, Jiang J (2011) Palladium nanoparticle/chitosan-grafted graphene nanocomposites for construction of a glucose biosensor. Biosens Bioelectron 26:3456–3463

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Biotechnology Engineering, Faculty of Engineering, International Islamic University Malaysia, Kuala Lumpur, Malaysia

    Farrah Aida Arris, Abdel Mohsen Benoudjit, Fahmi Sanober & Wan Wardatul Amani Wan Salim

Authors
  1. Farrah Aida Arris
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  2. Abdel Mohsen Benoudjit
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  3. Fahmi Sanober
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  4. Wan Wardatul Amani Wan Salim
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Corresponding author

Correspondence to Wan Wardatul Amani Wan Salim .

Editor information

Editors and Affiliations

  1. International Institute for Halal Research and Training (INHART), International Islamic University Malaysia, Kuala Lumpur, Malaysia

    Azura Amid

  2. Department of Biotechnology Engineering, Kulliyyah of Engineering, International Islamic University Malaysia, Kuala Lumpur, Malaysia

    Sarina Sulaiman

  3. Department of Biotechnology Engineering, Kulliyyah of Engineering, International Islamic University Malaysia, Kuala Lumpur, Malaysia

    Dzun Noraini Jimat

  4. Department of Biotechnology Engineering, Kulliyyah of Engineering, International Islamic University Malaysia, Kuala Lumpur, Malaysia

    Nor Fadhillah Mohamed Azmin

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Arris, F.A., Benoudjit, A.M., Sanober, F., Wan Salim, W.W.A. (2018). Characterization of Electrochemical Transducers for Biosensor Applications. In: Amid, A., Sulaiman, S., Jimat, D., Azmin, N. (eds) Multifaceted Protocol in Biotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-13-2257-0_11

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