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Endoscopic Diagnosis

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Book cover Gastric Cancer

Abstract

The strategy of early detection and early treatment of gastric cancer to reduce the mortality rate has been widely implemented in Japan. To detect early-stage gastric cancer, considerable education regarding endoscopic methods for systematic screening is carried out. If suspicious lesions for gastric cancer are detected by conventional white-light imaging, a detailed differential diagnosis of cancerous and non-cancerous lesions by image-enhancement endoscopy with/without magnification, followed by biopsy, is performed as a usual subsequent approach. In the case of lesions diagnosed as cancer by histology, a endoscopist performs a detailed examination before treatment to define the (1) histological type, (2) tumor size, (3) presence and absence of ulceration or scar, and (4) depth of invasion to determine the treatment indication, i.e., endoscopic or surgical. Regarding the tumor size, the boundary of the lesion should be precisely identified in order to determine the excision line. Recently, the ABC method using a combination of serum Helicobacter pylori antibody and pepsinogen tests, which involves an overview of risk stratification of gastric cancer, is recommended as a part of gastric cancer screening.

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Nagahama, T., Uedo, N., Yao, K. (2019). Endoscopic Diagnosis. In: Shiotani, A. (eds) Gastric Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-13-1120-8_9

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  • DOI: https://doi.org/10.1007/978-981-13-1120-8_9

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