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Pathology of Ovary: Sex Cord Tumours

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Color Atlas of Female Genital Tract Pathology
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Abstract

This chapter provides illustrations and descriptions of pure sex cord tumours, pure stromal tumours and mixed sex cord stromal tumours of ovary. In addition to the gross and microphotographs of these tumours, the salient clinical, gross, immunohistochemistry and molecular pathology of these tumours are also described.

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Suggested Reading

  • Atram M, Anshu SS, Gangane N. Sclerosing stromal tumour of the ovary. Obstet Gynecol Sci. 2014;57(5):405–8.

    Article  Google Scholar 

  • Bennett JA, Oliva E, Young RH. Sclerosing stromal tumours with prominent luteinization during pregnancy: a report of 8 cases emphasizing diagnostic problems. Int J Gynecol Pathol. 2015;34:357–62.

    Article  Google Scholar 

  • Burandt E, Young RH. Thecoma of the ovary: a report of 70 cases emphasizing aspects of its histopathology different from those often portrayed and its differential diagnosis. Am J Surg Pathol. 2014;38(8):1023–32.

    Article  Google Scholar 

  • Dal Cin P, Pauwels P, Van den Berghe H. Fibrosarcoma versus cellular fibroma of the ovary. Am J Surg Pathol. 1998;22(4):508–10.

    Article  CAS  Google Scholar 

  • Geetha P, Nair MK. Granulosa cell tumours of the ovary. Aust N Z J Obstet Gynaecol. 2010;50(3):216–20.

    Article  Google Scholar 

  • Haroon S, Idrees R, Fatima S, Memon A, Kayani N. Ovarian steroid cell tumour, not otherwise specified: a clinicopathological and immunohistochemical experience of 12 cases. J Obstet Gynaecol Res. 2015;41(3):424–31.

    Article  Google Scholar 

  • Hayes MC, Scully RE. Ovarian steroid cell tumour (not otherwise specified): a clinicopathological analysis of 63 cases. Am J Surg Pathol. 1987;11:835–45.

    Article  CAS  Google Scholar 

  • Hayes MC, Scully RE. Stromal luteoma of the ovary: a clinicopathological analysis of 25 cases. Int J Gynecol Pathol. 1987;6:313–21.

    Article  CAS  Google Scholar 

  • Irving JA, Alkushi A, Young RH, Clement PB. Cellular fibromas of the ovary: a study of 75 cases including 40 mitotically active tumours emphasizing their distinction from fibrosarcoma. Am J Surg Pathol. 2006;30:928–38.

    Article  Google Scholar 

  • Koukourakis GV, Kouloulias VE, Koukourakis MJ, Zacharias GA, Papadimitriou C, Mystakidou K, Pistevou-Gompaki K, Kouvaris J, Gouliamos A. Granulosa cell tumour of the ovary: tumour review. Integr Cancer Ther. 2008;7(3):204–15.

    Article  Google Scholar 

  • Kozan P, Chalasani S, Handelsman DJ, Pike AH, Crawford BA. A Leydig cell tumour of the ovary resulting in extreme hyperandrogenism, erythrocytosis, and recurrent pulmonary embolism. J Clin Endocrinol Metab. 2014;99(1):12–7.

    Article  CAS  Google Scholar 

  • Mancari R, Portuesi R, Colombo N. Adult granulosa cell tumours of the ovary. Curr Opin Oncol. 2014;26(5):536–41.

    Article  Google Scholar 

  • Numanoglu C, Guler S, Ozaydin I, Han A, Ulker V, Akbayir O. Stromal luteoma of the ovary: a rare ovarian pathology. J Obstet Gynaecol. 2015;35(4):420–1.

    Article  CAS  Google Scholar 

  • Prat J, Young RH, Scully RE. Ovarian Sertoli-Leydig cell tumours with heterologous elements. II. Cartilage and skeletal muscle: a clinicopathologic analysis of twelve cases. Cancer. 1982;50(11):2465–75.

    Article  CAS  Google Scholar 

  • Roth LM, Anderson MC, Govan ADT, et al. Sertoli-Leydig cell tumours: a clinicopathologic study of 34 cases. Cancer. 1981;48:187–97.

    Article  CAS  Google Scholar 

  • Scully RE. Juvenile granulosa cell tumour. Pediatr Pathol. 1988;8(4):423–7.

    Article  CAS  Google Scholar 

  • Shah SP, Kobel M, Senz J, et al. Mutation of FOXL2 in granulosa-cell tumours of the ovary. N Engl J Med. 2009;360:2719–29.

    Article  CAS  Google Scholar 

  • Shanthala PR, Saldhana P, Upadhyaya K. Gynandroblastoma: a rare ovarian tumour with an unusual clinical presentation. J Indian Med Assoc. 2014;112(2):128, 130.

    PubMed  Google Scholar 

  • Stellato G, Di Bonito M, Tramontana S. Primary fibrosarcoma of the ovary. Acta Obstet Gynecol Scand. 1995;74(8):649–52.

    Article  CAS  Google Scholar 

  • Stuart GC, Dawson LM. Update on granulosa cell tumours of the ovary. Curr Opin Obstet Gynecol. 2003;15(1):33–7.

    Article  Google Scholar 

  • Young RH. Ovarian sex cord-stromal tumours and their mimics. Pathology. 2018;50(1):5–15.

    Article  CAS  Google Scholar 

  • Young RH, Dickersin GR, Scully RE. Juvenile granulosa cell tumour of the ovary. A clinicopathological analysis of 125 cases. Am J Surg Pathol. 1984;8:575–96.

    Article  CAS  Google Scholar 

  • Zhang HY, Zhu JE, Huang W, Zhu J. Clinicopathologic features of ovarian Sertoli-Leydig cell tumours. Int J Clin Exp Pathol. 2014;7(10):6956–64.

    PubMed  PubMed Central  Google Scholar 

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Dey, P. (2019). Pathology of Ovary: Sex Cord Tumours. In: Color Atlas of Female Genital Tract Pathology. Springer, Singapore. https://doi.org/10.1007/978-981-13-1029-4_8

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  • DOI: https://doi.org/10.1007/978-981-13-1029-4_8

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-13-1028-7

  • Online ISBN: 978-981-13-1029-4

  • eBook Packages: MedicineMedicine (R0)

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