Abstract
We study the time-dependent distribution of blood platelet size, and its process of evolution with time, when treated with a mobile ion-carrier chemical A23187 that can penetrate into the cells causing size breakdown. The study helps to understand the role of A23187 as a carrier of drugs into cells, and to investigate signaling pathway in platelets that is of relevance in diagnosing diseases like brain stroke, diabetes, etc. It appears that the size distribution of platelets stabilizes after a time period of 3 h and more. Growth pattern of peak and ebb of the time-dependent platelet size distributions is studied to examine the stability of the process in the long run. A proportionate growth model of size breakdown is proposed.
The original version of this chapter was revised: Authors’ names and their affiliations have been included. The correction to this chapter is available at https://doi.org/10.1007/978-981-13-0980-9_12
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Change history
28 December 2018
The original version of the chapter was inadvertently published without authors’ names and their affiliations, Dr. Koushik Biswas, Regional Institute of Ophthalmology, Medical College Hospital, Kolkata-700073, India. Email: koushik2907@gmail.com and Dr. Debabrata Dash, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India. Email: ddash.biochem@gmail.com in the opening page of chapter “A Statistical Study of Platelet Size Decomposition and Related Growth Model”, which have now been included. The correction chapter and the book have been updated with the changes.
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Dasgupta, R., Biswas, K., Dash, D. (2018). A Statistical Study of Platelet Size Decomposition and Related Growth Model. In: Dasgupta, R. (eds) Advances in Growth Curve and Structural Equation Modeling. Springer, Singapore. https://doi.org/10.1007/978-981-13-0980-9_11
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DOI: https://doi.org/10.1007/978-981-13-0980-9_11
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