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Cutting-Edge Enabling Technologies for Regenerative Medicine pp 3–14Cite as

3D Bioprinting of Adipose-Derived Stem Cells for Organ Manufacturing

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1078))

Abstract

Organ manufacturing is an attractive high-tech research field which can solve the serious donor shortage problems for allograft organ transplantation, high throughput drug screening, and energy metabolism model establishment. How to integrate heterogeneous cell types along with other biomaterials to form bioartificial organs is one of the kernel issues for organ manufacturing. At present, three-dimensional (3D) bioprinting of adipose-derives stem cell (ADSC) containing hydrogels has shown the most bright futures with respect to overcoming all the difficult problems encountered by tissue engineers over the last several decades. In this chapter, we briefly introduce the 3D ADSC bioprinting technologies for organ manufacturing, especially for the branched vascular network construction.

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Acknowledgments

The work was supported by grants from the National Natural Science Foundation of China (NSFC) (No. 81571832 & 81271665), the 2017 Discipline Promotion Project of China Medical University (CMU) (No. 3110117049), and the International Cooperation and Exchanges NSFC and Japanese Society for the Promotion of Science (JSPS) (No. 81411140040).

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Authors and Affiliations

  1. Center of Organ Manufacturing, Department of Tissue Engineering, China Medical University (CMU), Shenyang, People’s Republic of China

    Xiaohong Wang

  2. Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, Beijing, People’s Republic of China

    Xiaohong Wang

  3. Tianjin Mifang Technology Company Limited, Tianjin, People’s Republic of China

    Chang Liu

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  1. Xiaohong Wang
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  2. Chang Liu
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Correspondence to Xiaohong Wang .

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Editors and Affiliations

  1. The Catholic University of Korea, Seoul, Korea (Republic of)

    Heung Jae Chun

  2. Hallym University, Gangwon-do, Korea (Republic of)

    Chan Hum Park

  3. Kyung Hee University, Seoul, Korea (Republic of)

    Il Keun Kwon

  4. Chonbuk National University, Jeonju, Korea (Republic of)

    Gilson Khang

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Wang, X., Liu, C. (2018). 3D Bioprinting of Adipose-Derived Stem Cells for Organ Manufacturing. In: Chun, H., Park, C., Kwon, I., Khang, G. (eds) Cutting-Edge Enabling Technologies for Regenerative Medicine. Advances in Experimental Medicine and Biology, vol 1078. Springer, Singapore. https://doi.org/10.1007/978-981-13-0950-2_1

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