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Roles of Single Cell Systems Biomedicine in Lung Diseases

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Single Cell Biomedicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1068))

Abstract

Single cell sequencing is important to detect the gene heterogeneity between cells, as the part of single-cell systems biology which combines computational science, mathematical modelling and high-throughput technologies with biological function and organization in the cell. We initially arise the question how to integrate the outcomes of single-cell systems biology with clinical phenotype, interpret alterations of single-cell gene sequencing and function in patient response to therapies, and understand the significance of single-cell systems biology in the discovery and development of new molecular diagnostics and therapeutics. The present review furthermore focuses the significance of singe cell systems biology in respiratory diseases and calls the special attention from scientists who are working on single cell systems biology to improve the diagnosis and therapy for patients with lung diseases.

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Author information

Author notes

  1. Authors Yiming Zeng and Xiaoyang Chen have equally contributed to this chapter as the first author.

Authors and Affiliations

  1. Department of Respiratory Pulmonary and Critical Care Medicine, The Second Hospital of Fujian Medical University, Quanzhou, Fujian Province, China

    Yiming Zeng, Xiaoyang Chen & Xiangdong Wang

Authors
  1. Yiming Zeng
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  2. Xiaoyang Chen
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  3. Xiangdong Wang
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Corresponding author

Correspondence to Xiangdong Wang .

Editor information

Editors and Affiliations

  1. Henan Provincial People’s Hospital, Zhengzhou, Henan, China

    Jianqin Gu

  2. Shanghai Institute of Clinical Bioinformatics, Zhongshan Hospital, Fudan University, Shanghai, China

    Xiangdong Wang

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© 2018 Springer Nature Singapore Pte Ltd.

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Zeng, Y., Chen, X., Wang, X. (2018). Roles of Single Cell Systems Biomedicine in Lung Diseases. In: Gu, J., Wang, X. (eds) Single Cell Biomedicine. Advances in Experimental Medicine and Biology, vol 1068. Springer, Singapore. https://doi.org/10.1007/978-981-13-0502-3_15

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