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LHRH Agonist and Antagonist for Prostate Cancer

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Management of Advanced Prostate Cancer

Abstract

ADT is the main treatment for advanced prostate cancer. Combination therapy with radiotherapy in early stage prostate cancer is increasing. LHRH agonists are the most frequently used type of ADT for several years, and they have suppressed the serum testosterone to castration level in almost all patients. Furthermore, LHRH antagonist was developed recently as an alternative form of ADT with direct and immediate suppression of testosterone without initial testosterone flare phenomenon. Therefore, in this chapter, we will describe the comparative efficacy and safety between LHRH agonists and LHRH antagonists for prostate cancer.

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Authors and Affiliations

  1. Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, South Korea

    Jin Bong Choi & Jun Sung Koh

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  1. Jin Bong Choi
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  2. Jun Sung Koh
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Correspondence to Jun Sung Koh .

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Editors and Affiliations

  1. Department of Urology, Asan Medical Center, Seoul, Soul-t´ukpyolsi, Korea (Republic of)

    Choung Soo Kim

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© 2018 Springer Nature Singapore Pte Ltd.

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Choi, J.B., Koh, J.S. (2018). LHRH Agonist and Antagonist for Prostate Cancer. In: Kim, C. (eds) Management of Advanced Prostate Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-10-6943-7_15

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  • DOI: https://doi.org/10.1007/978-981-10-6943-7_15

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-6942-0

  • Online ISBN: 978-981-10-6943-7

  • eBook Packages: MedicineMedicine (R0)

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