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Activator Protein-1 Transcription Factors in Pathological Cancers

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Role of Transcription Factors in Gastrointestinal Malignancies

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Abstract

Activator protein-1 transcription factors play a critical role in the development of many cancers. Although many studies indicated the role of transcription factors driving the progression of cancer, there is still a knowledge gap in the process of better understanding the molecular mechanisms controlled by AP-1 transcription factors during cancer advancement. In conclusion, we have evaluated the role of transcription factors which provides new insights into mechanisms of regulation of colorectal cancer by AP-1 family transcription factors.

The original version of this chapter was revised. The book was inadvertently published without Abstracts and Keywords, which are now included in all the chapters. An erratum to this chapter can be found at https://doi.org/10.1007/978-981-10-6728-0_39

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Abbreviations

%:

Percent

AP-1:

Activator protein-1

ATF:

Activating transcription factor

CRC:

Colorectal cancer

MAF:

Musculoaponeurotic liposarcoma

TPA:

12-O-tetradecanoylphorbol-13-acetate

TRE:

TPA-response element

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Author information

Authors and Affiliations

  1. Department of Medical Imaging, Sangre Grande General Hospital, Sangre Grande, Trinidad and Tobago

    Siva Krishna Prasad Konduru

  2. Dr. LV Prasad Diagnostics and Research Laboratory, Hyderabad, Telangana, India

    Ganji Lakshmi Vara Prasad

  3. Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA-30322, USA

    Neha Merchant

  4. Department of Molecular Cardiology, Cleveland Clinic, Cleveland, OH, USA

    Santoshi Muppala

Authors
  1. Siva Krishna Prasad Konduru
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  2. Ganji Lakshmi Vara Prasad
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  3. Neha Merchant
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  4. Santoshi Muppala
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Corresponding author

Correspondence to Santoshi Muppala .

Editor information

Editors and Affiliations

  1. Department of Hematology and Medical Oncology, Emory University, Atlanta, Georgia, USA

    Ganji Purnachandra Nagaraju

  2. Department of Biotechnology, Krishna University, Machilipatnam, Andhra Pradesh, India

    Pallaval Veera Bramhachari

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Konduru, S.K.P., Prasad, G.L.V., Merchant, N., Muppala, S. (2017). Activator Protein-1 Transcription Factors in Pathological Cancers. In: Nagaraju, G., Bramhachari, P. (eds) Role of Transcription Factors in Gastrointestinal Malignancies. Springer, Singapore. https://doi.org/10.1007/978-981-10-6728-0_16

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