Abstract
Several clinical states may show a decrease of the circulating E-rosette forming cells. We observed that the lymphocytes with a reduced E-rosette forming power when incubated in vitro with levamisole either showed an increase in number to the normal values or the E-rosette forming cells did not change. This last group was less frequent and was found in clinical situations compatible with true thymus-dependent T cell depletion (leukaemia, Hodgkin’s disease, LES). Frequently the incubation of lymphocytes with levamisole was promptly followed by a normalization of the E-rosette forming cells.
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© 1980 MTP Press Limited
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Pasini, F.L., Auteri, A., Di Perri, T. (1980). Levamisole and thymopoietin pentapeptide (TP5) correction of E-rosette depression in man: in vitro and in vivo studies. In: Willoughby, D.A., Giroud, J.P. (eds) Inflammation: Mechanisms and Treatment. Inflammation: Mechanisms and Treatment, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9423-8_83
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DOI: https://doi.org/10.1007/978-94-010-9423-8_83
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-9425-2
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